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RESEARCH JOURNAL OF TOPICAL AND COSMETIC SCIENCES
Year : 2020, Volume : 11, Issue : 2
First page : ( 59) Last page : ( 61)
Print ISSN : 0976-2981. Online ISSN : 2321-5844.
Article DOI : 10.5958/2321-5844.2020.00010.2

Antioxidant activity of Malvastrum coromandelianum leaf extracts

Yadav Akshay R.1*, Mohite Shrinivas K.1

1Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India-415404.

*Corresponding Author E-mail: akshayyadav24197@gmail.com

Online published on 10 February, 2021.

Abstract

Malvastrum coromandelianum belongs to Malvaceae family, commonly known as the false mallow. Ethnobotanical survey reported its use in the treatment of various disorders. Pharmacological screening has shown the plant to have anti-inflammatory, analgesic, and antibacterial activity. Antioxidants or inhibitors of oxidation are compounds which retard or prevent the oxidation and in general prolong the life of the oxidizable matter. Majority of the diseases/disorders are mainly linked to oxidative stress due to free radicals. The free radicals (oxidants) are species with very short half-life, high reactivity and damaging activity towards macromolecules like proteins, DNA and lipids. In general, the reactive oxygen species circulating in the body tend to react with the electron of other molecules in the body and these also effect various enzyme systems and cause damage which may further contribute to conditions such as cancer, ischemia, aging, adult respiratory distress syndromes, rheumatoid arthritis etc. A plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants. It has been hypothesized that plant antioxidants may contribute to the beneficial health effects of dietary plants. The results of the free radical scavenging activity of the DPPH radical assay method for antioxidant activity have shown that the Malvastrum coromandelianum leaf extracts exhibits significant scavenging activity.

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Keywords

Malvastrum coromandelianum, DPPH radical assay method, Antioxidant activity.

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