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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 8
First page : ( 1036) Last page : ( 1038)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00196.7

Detection of fimbriae mediated adhesion/mannose resistant hemagglutinin among urinary isolates of Escherichia coli

Sridhar M., Gopinath P.*

Department of Microbiology, Saveetha Dental College and Hospital, Chennai, Tamilnadu, India

*Corresponding Author E-mail: gopu.myco@gmail.com

Online published on 12 January, 2017.

Abstract

Background

E.coli is the most frequent urinary pathogen isolated from 50–90% of all uncomplicated UTI's. E.coli present in the gastrointestinal tract as commensals provide the proof for the initiation of UTI. In the late 1970’s it was recognised for the first time that E.coli strain causing UTI typically agglutinate human RBC's despite the presence of mannose and this was mediated by fimbriae which serves as a virulence factor.

Materials and Methods

A sum of 20 isolates of E.coli is obtained from suspected cases of UTI which will be subjected for antibiotic susceptibility testing and presence of mannose resistant hemagglutinin by hemagglutination assay.

Result

Out of 20 clinical isolates of E.coli, 4/20 (20%) isolates from acute cases of UTI and 2/20 (10%) strained received from chronic UTI cases also showed mannose resistant hemagglutinin.

Conclusion

Our study reveals, there was a association between presence of Type 1 fimbriae and UTI. These isolates were also resistant to multiple antibiotics represents that, there is a need for judicial usage of antibiotics for the proper clinical outcome.

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