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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 7
First page : ( 942) Last page : ( 944)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00181.5

Formulation, evaluation and release studies of Indomethacin Suppositories

Dewangan Kalyani1, Nagori Kushagra1, Sharma Mukesh1, Singh Ajay2, Chandrakar Sandhya1, Sahu Vandana Devi1, Sharma Garima1, Gupta Sujata1, Solanki Harsha1, Majumdar Manisha1, Tripathi D. K.1, Alexander Amit1, Ajazuddin1,*

1Rungta College of Pharmaceutical Sciences and Research, Kurud Road Kohka, Bhilai, Chhattisgarh, India, 490024

2GD Rungta College of Science and Technology, Kurud Road Kohka, Bhilai, Chhattisgarh, India, 490024

*Corresponding Author E-mail: ajazuddin@rungta.ac.in

Online published on 15 October, 2016.


Indomethacin suppositories were prepared by using water soluble bases. All the prepared suppositories were evaluated for various physical parameters like weight variation, hardness, Liquefaction time. In-vitro release study was performed USP type I apparatus (Basket type) using phosphate buffer pH 7.4 as dissolution media. The suppositories prepared were within permissible range of all physical parameters.



Indomethacin, suppositories, Liquefaction time.


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