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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 7
First page : ( 761) Last page : ( 763)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00144.X

Spectroscopic Determination and Validation of Rosuvastatin Calcium Concentration in Bulk and Dosage form

Katkade Pramod Nanasaheb1,*, Saudagar Ravindranath Bhanudas2

1Department of Pharmacy, Pacific University, Udaipur, Rajasthan-313003

2Department of Quality Assurance Techniques, KCT's R. G. Sapkal College of Pharmacy, Anjaneri, Nashik

*Corresponding Author E-mail: pramod_katkade@rediffmail.com

Online published on 15 October, 2016.

Abstract

A simple, accurate, precise, and sensitive a highly selective ultra violet spectrophotometric method has been developed for the estimation of Rosuvastatin Calcium in bulk and dosage form. It shows maximum absorbance at 242.8nm. The Beer-Lambert's law was obeyed in the concentration range of 8–32μg/ml. The linear regression analysis data for calibration plots showed good linear relationship and obtain correlation factor for Rosuvastatin Calcium. The percentage recovery was found to be within range. Thus method was successfully applied for routine analysis of Rosuvastatin Calcium in bulk drug and dosage form.

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Keywords

Rosuvastatin Calcium, UV-method, Spectrometric method, Determination.

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