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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 6
First page : ( 755) Last page : ( 758)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00143.8

Evaluation of In-vitro Anti-Inflammatory activity of Petroleum Ether Extract of Butea monosperma Flowers

Yerragunta Vishwanadham1,*, Saba Ayesha2, Sadia Ayesha2, Begam Amreen2, Fatima Syeda Kausar2, Nausheen Hajera3, Reddy E. Sathish2

1Vishnu Institute of Pharmaceutical Education and Research, Narsapur, Medak, Telangana, India

2PNR College of Pharmacy, Shamshabad, Rangareddy, Telangana, India

3Azad College of Pharmacy, Moinabad, Rangareddy, Telangana, India

*Corresponding Author E-mail: vishwanadham.y@gmail.com

Online published on 21 July, 2016.

Abstract

Butea monosperma is a species of Butea native to tropical and sub-tropical parts of the Indian Subcontinent and Southeast Asia, ranging across India. Common names include flame-of-the-forest and bastard teak. Butea monosperma is investigated for antibacterial activity, anti -inflammatory activity. From the study of all the activities already done, the authors found out that anti -rash or anti-allergic activity is not investigated. Dried flowers of Butea monosperma were extracted using Petroleum ether using continuous soxhlet extraction apparatus. The extract was evaporated to dryness using rota evaporator followed by drying in the desiccator. This dry extract was treated as whole drug and tested for in-vitro anti-inflammatory activity using Carrageenan induced rat paw edema method with Diclofenac sodium as standard drug. Successful in-vitro results were confirmed by animal study where anti-inflammatory activity was proved on Male Wistar albino rats.

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Keywords

Butea monosperma, In-vitro anti-inflammatory activity, Petroleum ether, Diclofenac sodium.

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