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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 5
First page : ( 559) Last page : ( 561)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00106.2

Phytochemical Composition of Methanolic Extract of Phyllanthus acidus L (Skeels) Fresh Leaves by GC/MS Analysis

Phatak Rohan Sharadanand1,*, Hendre Anup Subhash2, Durgawale Pushpa Prakash2

1Directorate of Research, Krishna Institute of Medical Sciences Deemed University, Malkapur, Karad-415539, India

2Department of Biochemistry, Krishna Institute of Medical Sciences, Malkapur, Karad-415539, India

*Corresponding Author E-mail: phatak.rohan1983@gmail.com

Online published on 21 June, 2016.

Abstract

Background

Secondary metabolites and different phytochemicals are present in the medicinal plant Phyllanthus acidus belonging to family Phyllanthaceae. Scientific evidence data related GC-MS analysis of methanolic extract of Phyllanthus acidus fresh leaves has not been reported till date during literature review.

Objective

The study was aimed to investigate phytochemicals present in the methanolic extract of Phyllanthus acidus fresh leaves.

Material and Methods

Methanolic extraction of fresh leaves Phyllanthus acidus was prepared by simple maceration and GC-MS analysis data was provided by IICPT, Thanjavur. Phytochemical investigation was carried out to identify the possible components from Phyllanthus acidus fresh leaves by evaluating retention time in the GC-MS chromatogram.

Results

Eleven peaks have revealed in the GC-MS spectrum of the methanolic extract of Phyllanthus acidus. From the results, squalene is present as major bioactive compounds in methanolic extract of Phyllanthus acidus fresh leaves.

Conclusion

The present data provides to find the molecular formula and weight of 11 biomolecules. Further investigation should be done to isolate bioactive compounds and their structural elucidation and screening of pharmacological activity in the drug development.

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Keywords

GC/MS analysis, Phytochemicals, Phyllanthus acidus.

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