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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 5
First page : ( 490) Last page : ( 492)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00090.1

Validated UV-Spectroscopic estimation of Linagliptin Concentration in Bulk and Dosage form

Zalte Amar Gangadhar1, Saudagar Ravindranath Bhanudas1, Katkade Pramod Nanasaheb2,*

1KCT's R. G. Sapkal College of Pharmacy, Anjaneri, Nashik

2Department of Pharmacy, Pacific University, Udaipur, Rajasthan-313003

*Corresponding Author E-mail: pramod_katkade@rediffmail.com

Online published on 21 June, 2016.

Abstract

A simple, accurate, precise, sensitive and a highly selective ultra violet spectrophotometric method has been developed for the simultaneous estimation of Linagliptin Concentration in bulk and solid dosage form. The estimation of Linagliptin was carried out at 297 nm. The developed method was validated for linearity, range, precision, recovery studies and interference study for mixture. All these parameters showed the adaptability of the method for the quality control analysis of the drug in bulk and in marketed formulations.

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Keywords

Linagliptin, UV-method, Spectrometric method, Determination.

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