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Research Journal of Pharmacy and Technology
Year : 2016, Volume : 9, Issue : 2
First page : ( 128) Last page : ( 130)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2016.00020.2

Screening of Antibacterial Activity In Vitro of Eryngium creticum

Mansour Oussama1,*, Darwish Manal2, Ismail Ghenwa3, Harfouch Rim4, Ali Rabab Shikh2, Deeb Zain2

1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syria

2Department of Pharmacognosy, Faculty of Pharmacy, Al Andalus University, Tartous, Syria

3Department of Pharmaceutics, Faculty of Pharmacy, Al Andalus University, Tartous, Syria

4Department of Microbiology, Faculty of Pharmacy, Al Andalus University, Tartous, Syria

*Corresponding Author E-mail: mansouroussama@yahoo.fr

Online published on 9 March, 2016.

Abstract

This study was conducted to evaluate the antimicrobial activity of tow extract of Eryngium creticum plant belonging to the Apiaceae family collected from the coastal surrounding, Tartous, Syria. Many efforts have been made to discover new antimicrobial activity from a variety of sources such as micro-organisms, animals and plants. One such source is Folk medicine. Systematic screening of them may result in the discovery of new effective compounds. These extracts were prepared with polar solvent (methanol and ethanol) by steeping extraction method. The antimicrobial activity of the extracts was assessed using the disk diffusion method against gram-positive (Staphylococcus aureus), and gram-negative (Escherichia coli) bacteria. The methanolic extracts of Eryngium creticum have shown antimicrobial activity against tested bacteria. The activity was compared with potent broad spectrum antibiotics such as Cefipime, Amecasine and ceftriaxon.

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Keywords

Eryngium Creticum, disk diffusion method, antimicrobial activity, extracts, Staphylococcus aureusEscherichia coli.

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