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Research Journal of Pharmacy and Technology
Year : 2015, Volume : 8, Issue : 6
First page : ( 800) Last page : ( 810)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2015.00129.8

Emerging Pressurized Liquid Extraction (PLE) Techniques as an Innovative Green Technologies for the Effective Extraction of the Active Phytopharmaceuticals

Raut Parijeeta1, Bhosle Divya1, Janghel Akshay1, Deo Shraddha1, Verma Chetan1, Kumar Shyama S.1, Agrawal Mukta1, Amit Nisha2, Sharma Mukesh1, Giri Tapan3, Tripathi D. K.1,  Ajazuddin1, Alexander Amit1,*

1Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, India, 490024

2Ex-Employee, Kalyan PG College, Sector 7, Bhilai, Chhattisgarh, India

3NSHM College of Pharmaceutical Technology, NSHM Knowledge Campus, Kolkata Group of Institutions, 124 BL Saha Road, Kolkata-700053, West Bengal, India

*Corresponding Author E-mail: itsmeamitalex@gmail.com

Online published on 30 July, 2015.


Pressurized liquid extraction (PLE) is a process that pools temperature and pressure with liquid solvents to accomplish rapid and efficient extraction of analytes from several matrices. PLE is a more recent extraction technique proposed to obtain bioactive compounds. It uses less solvent, in a shorter period of time, is automated, and involves retaining the sample in an oxygen and light-free environment in contrast to traditional organic solvent extraction. PLE is based on the use of conventional solvent set controlled temperatures and pressures and has been well established for extraction of valuable compounds from natural sources. A major benefit of PLE above conventional solvent extraction methods conducted at atmospheric pressure is that pressurized solvents remain in the liquid state, even above their normal atmospheric pressure boiling points allowing hightemperature. PLE is used for the extraction of many compounds in vegetal oil as lipids and fatty acids owing to its short time extraction. It also can be used in the extraction of minor components, such as anthocyanins, carotenoids, phenols, sterols, phospholipids, tocopherols, free fatty acids, and glycerides, because these compounds may be degraded during long extractions at higher temperatures. In the present study we have highlighted the recent findings associated with the PLE.



PLE, Extraction, herbals, bioactives, Standardization.


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