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Research Journal of Pharmacy and Technology
Year : 2015, Volume : 8, Issue : 12
First page : ( 1340) Last page : ( 1346)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2015.00312.1

Evaluation of controlled porosity osmotic pump tablets: A Review

Sahoo Chinmaya Keshari1,*, Rao Surepalli Ram Mohan2, Sudhakar Muvvala3

1Ph. D Scholar, Department of Pharmaceutics, Osmania University College of Technology, Osmania University, Hyderabad, Telangana, India

2Professor, Mekelle Institute of Technology, Mekelle University, Mekelle, Ethiopia

3Professor and Principal, Department of Pharmaceutics, Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad, Telangana, India

*Corresponding Author E-mail: Sahoo.chinmaya83@gmail.com

Online published on 1 January, 2016.

Abstract

The objective of present review was to determine the various evaluation tests for controlled porosity osmotic pump tablets. Controlled porosity osmotic pump (CPOP) tablet contains drug, osmogens, excipients in core and a coating of semi permeable membrane with water soluble additives. In CPOP water soluble additives dissolve after coming in contact with water, resulting in an in situ formation of micro porous membrane. CPOP tablets were evaluated for compatibility study, precompression parameters and post compression parameters. The present study gives an idea about various evaluation tests for CPOP tablets.

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Keywords

CPOP, Osmogens, Compatibility study, Precompression parameters, Post compression parameters.

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