Effect of Asoka Bark (Saraca indica) and Custard Apple Pulp (Annona squamosa) on Wound Healing in Female Albino Rats. Fathima H. Rihana, Reddy P. Neelakanta* Bio Organic Laboratory, Central Leather Research Institute, (Council of Scientific and Industrial Research), Adyar, Chennai-600020, Tamilnadu, India *Corresponding Author E-mail: neelakantareddyp@gmail.com
Online published on 3 April, 2013. Abstract Asoka tree Bark (Saraca indica) and Custard Apple pulp (Annona squamosa) has been shown to possess healing activity. The present work with these materials was undertaken with the promise that the drug promoting ulcers, boils healing could have effect on wound healing also. Wound healing activity of these materials was studied in terms of (i) Percent wound contraction epithelization; (ii) wound breaking strength; (iii) on granulation tissue formation and maturation (hydroxyproline, hexosamine, Lowry's, uronic levels) in excision wound respectively. The extract applied (100mg/kg) 10 times on the wounded surface in alternative days for a period of 16 days, both extracts (100mg/kg) when studied for excision wound parameters, increased wound breaking strength and levels of biochemical test when compared with the control group. Both the extracts showed good safety profile. In my study Asoka tree (Saraca indica) thus, favored wound healing faster than the (Annona squamosa) Custard Apple pulp fruit. Top Keywords Annona squamosa, Saraca indica, Wound healing, Biochemical parameters, Histology, Tensile strength. Top |