|
|
|
|
|
|
|
|
|
|
New Technologies in Particulate Engineering for Pulmonary Delivery of Macromolecule Pachoriya R*, Sharma A Department of Pharmaceutics, V.N.S Institute of Pharmacy, Neelbud, Bhopal (M.P.) India *Corresponding Author E-mail: rahul_pachoriya@yahoo.co.in
Online published on 3 April, 2013. Abstract As the end organ for the treatment of local diseases or as the route of administration for systemic therapies, the lung is a very attractive target for drug delivery. Pulmonary delivery of macromolecule provides direct access to disease in the treatment of respiratory diseases, while providing an enormous surface area and a relatively low enzymatic, controlled environment for systemic absorption of medication. Macromolecular Porous microparticle possess densities sufficient small to create aerodynamic particle sizes in the range of 1–5 μm, and for deep lung delivery 1–3 μm. To impart favorable aerodynamic properties, an effervescent technology provides encapsulate drug efficiently, sustained drug release, create porous scaffold for tissue engineering application. Top Keywords Macromolecule, Porous microparticle, Effervescent agents, Mucoadhesive agent, Dry powder inhaler. Top | |
|
|
|
|
║ Site map
║
Privacy Policy ║ Copyright ║ Terms & Conditions ║
 ║
|
|
|
834,229,451 visitor(s) since 30th May, 2005.
|
|
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
|
|
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.
|