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Research Journal of Pharmacy and Technology
Year : 2010, Volume : 3, Issue : 4
First page : ( 1170) Last page : ( 1174)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.

Evaluation of Phyto Pharmaceutical and Antioxidant Potential of Methanolic Extract of Peel of Punica granatum

Soni Himesh1,*, Nayak Govind1, Mishra Kaushelendra1, Singhai A.K.1, Pathak A.K.2

1Lakshmi Narain College of Pharmacy, Raisen Road, Bhopal (M.P.)-462021, India

2Department of Pharmacy, Barkatullah University, Bhopal-462026, India

*Corresponding Author E-mail: himeshsoni@rediffmail.com

Online published on 3 April, 2013.

Abstract

Pomegranate is the Fruit of Energy, Vitality and Medicinal Value. A number of medicinal uses has been reported some important once are, Anthelmintic Activity, Immuno -Stimulatory Activity, Hepato-Protective Activity, Antidiarrhoeal Activity, tumor growth inhibitory activity. The In-Vitro and In-Vivo antioxidant activity of peel of methanolic extract of Punica granatum has been investigated by 1,1, Diphenyl, 2-picryl hydrazyl free radical (DPPH), Reducing power and Nitric oxide, Lipid peroxidation scavenging Method. The methanolic extract of peel of Punica granatum showed significant antioxidant activity by inhibiting DPPH, Reducing power and when compared with standard ascorbic acid, antioxidant activity by Nitric oxide assay revealed that IC50 of Punica granatum was comparable with Standard (Curcumin) IC50, In-Vivo antioxidant activity Punica granatum on ethanol-induced changes were more or less similar and comparable with the vitamin C treatment.

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Keywords

Punica granatum, DPPH, antioxidant, Reducing power.

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