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Research Journal of Pharmacy and Technology
Year 2023, Volume-16, Issue-8 (August)
Print ISSN : 0974-3618
Online ISSN : 0974-360X

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Research Articles

In-vitro antioxidant and anti-aging activity of a traditional ayurvedic formulation
S. Shanthi, M. Sahina Begum, M. Senthuja

In vitro antiglycation activity of isorhamnetin on bovine serum albumin with different sugars using sodium dodecyl sulphate polyacrylamide gel electrophoresis
Sindhuja A, Vimalavathini R, Kuzhandai Velu V, Vickneshwaran V

Wound healing potential of formulated ointment by using virgin coconut oil in combination with Ethanol extract of Artocarpus lakoocha Roxb. leaves
Ibrenna G. Manik, Jansen Silalahi, Yuandani, Denny Satria

Design of some apigenin derivatives as selective DPP-IV inhibitors by pharmacophore modelling and its validation through molecular dynamics simulation
Ritika Sahu, Surendra Jain, Deepti Jain

Anxiolytic activity of coconut water by GABA modulation as evidenced by pharmacological experiments and molecular docking studies
Lakshmanan Ganesh, Deepa B, Shyamjith Manikkoth, Anuroopa G Nadh

Vitamin D as add on therapy to metformin and teneligliptin in patients with type 2 diabetes mellitus
Irfan Ahmad Khan, Shalini Chandra, Mohan Lal Kanojia

Prevention of psychological stress induced-ulcer in rats treated with fruit extract of Gymnospora montana
Kiran B. Kotade, Shivanand N. Hiremath, Santosh Ghule, Praveen Sharma, Tanvirsingh Rajput, Kiran B. Dhamak

Application of simplex lattice mixture design and desirability function in the development and optimization of sedds for protein kinase inhibitor-pazopanib hydrochloride
Amit Gupta, Rashmi Dahima

Behavioral, biochemical and histopathological evaluation of sinapic acid for antidepressant activity in normal mice and stressed mice
Sudha Bansal, Dinesh Dhingra

In vitro analysis of anticancer potential of green okra (Abelmoschus esculentus L.) polysaccharide extracts in HeLa cervical cancer cell line
Fina Syifa’una Musthoza, Raden Joko Kuncoroningrat Susilo, Suhailah Hayaza, Qurrotu A’yun, Nur’aini Fikriyah, Ufairanisa Islamatasya, Dwi Winarni, Sri Puji Astuti Wahyuningsih, Rueyan Doong, Deya Karsari, Aristika Dinar Yanti, Aulia Umi Rohmatika, Win Darmanto

Analytical correlation of laboratory tests with clinical findings in cases of paraproteinemia
Emilin Zacharias, Poornima A Manjrekar, Sowndarya K, Sindhu

Understanding the global transmission and demographic distribution of Nipah virus (NiV)
Md. Rezwan Ahmed Mahedi, Anurag Rawat, Fazle Rabbi, K. Suresh Babu, Elias Salvador Tasayco, Franklin Ore Areche, Olga Vicentina Pacovilca-Alejo, Denis Dante Corilla Flores, Salomón Vivanco Aguilar, Fredmoore L. Orosco, Nikolaos Syrmos, Mustafa Mudhafar, Sadia Afrin, Mst. Mahfuza Rahman

Investigation of In-vitro antiproliferative activity of ampelocissus latifolia root extract on MCF-7 breast cancer cells ampelocissus latifolia root extract against MCF-7 breast cancer cells
Nidarsan Viswanathan, V Gowri, K Punnagai

Gene expression of ACE2 gene in patients infected with COVID-19 and comparing them with vaccine recipients
Maryam Abdul Kareem Mahmoud, Nagam Khudhair

Acceptance of COVID -19 vaccines and associated barriers among dental students at college of Dentistry, University of Basrah: A cross-sectional study
Sarah A. Haji, Raed Taha Alneama, Najwan Sadik Shareef Al-Ghazzawi

In vitro and In vivo study of gastroprotective effect of purified extract Andrographis paniculata
Jastria Pusmarani, Citra Dewi, Risky Juliansyah Putri, Nur Hatidjah Awaliyah Halid, Sasri Intan Febriani, Febrianti Husni, Setyo Purwono, Zullies Ikawati

Design, synthesis and therapeutic investigation of tryptamine derivatives as potential antioxidant and amyloid inhibitor/disaggregator
Saira Asghar, Nousheen Mushtaq, Ahsaan Ahmad, Rabya Munawwar, Sumaira Ansari, Syeda Abiha Rizvi

Spectrophotometric method development and validation for determination of pazopanib in the bulk and the formulation
Ramendu Mishra, Anjana Devi

The role of robusta green bean extract in decreasing Il-1β levels on dental pulp stem cells (Dpsc) induced by lps porphyromonas gingivalis
Irma Josefina Savitri, Hendi Tri Medianto, Neira Najatus Sakinah, Amelia Putri Priambodo, Vinda Putri Kalista, Padmini Hari, Ernie Maduratna1

Knowledge towards COVID-19 preventive measures, and beliefs on use of herbal products as protective measure against COVID-19 infection
Nurliyana Najihah Binti Mazlan, Raja Ahsan Aftab, Nor Safwan Hadi Nor Afendi, Santhanathan A/L S. Rajendram, Sreenivas Patro Sisinthy

Molecular docking study on phytochemical profiling of trichosanthes dioica (Pointed gourd) against antitumor evaluation as cyclin dependent kinase -2(CDK2) inhibitors
B. Brindha, R. Girija

Evaluvation of anti-amnesic activity of ayurvedic formulation saraswathaghrita in the scopolamine-induced rat model
Haritha P H, T. Lakshmi Narayanan, Amrita Babu, G. Ariharasivakumar, Dithu Thekkekkara

Development and characterization of self-micro emulsifying drug delivery system of cilnidipine using simplex centroid mixture design
Payal N. Vaja, Chetan H. Borkhataria, Moinuddin M. Soniwala, Vidhi K. Matariya

Effect of coffee-corn mix on hypertensive mice on biomarkers of nitric oxide, enos, sodium, and ACE serum levels
Sugiyanta Sugiyanta, Harianto Notopuro, Jusak Nugraha

Proximate and micronutrient analysis of the leaf extracts of some Indian Medicinal plants from western Maharashtra
S. M. Pawaskar, H. Shah

Phytochemical analysis and identification of bio-active compounds in ethanolic leaf extract of Amaranthus spinosus
Sangita Boro, Bhriganka Bharadwaj, Balagopalan Unni, Avdhesh Kumar Rai, Minakshi Bhattacharjee

Analytical quality by design (QbD) approach for development and validation of HPLC method for acyclovir: Application degradation kinetics
Pallavi M. Patil, Vitthal V. Chopade, Surbhi C. Gupta

In-vivo estimation of optimized floating microspheres design by QBD approach
Pritam Rajkumar Siraskar, Dinesh Kumar Mishra

Anatomical variations of the paranasal sinuses in javanese patients with chronic rhinosinuitis
Asma, Irwan Kristyono, Baharudin Abdullah

Antifungal activity of Terminalia chebula extract against wilt fungi Fusarium oxysporum an important plant pathogen
Padmalatha A, Prabha S.B

Screening of phytochemical and quantitative lipase inhibition of honey and cinnamon paste: A synergistic effect
Pavithra R C, Arun A, Kanimozhi S

Development and validation of simultaneous equation method for estimation of sitagliptin phosphate and empagliflozin in bulk form by UV spectroscopy
Akanksha Dwivedi, Rajesh Sharma

Characteristics of edible film chitosan with glycerol as pasticizer
Eka Saputra, Wahju Tjahjaningsih, Annur Ahadi Abdillah, Viol Dhea Kharisma

Analytical RP-HPLC method development and validation for simultaneous estimation of Emtricitabine, Tenofovir and Bictegravir
A. Raja Reddy, R. Devicharan, T. Rama Rao

Anti-inflammatory activity and cyclooxygenase-2 inhibitory effect of Peperomia pellucida (L.) kunth extract
Ifora Ifora, Dian Oktaviani, Fitra Fauziah, Tosi Rahmaddian

Preparation and evaluation of in-house fabricated floating tablets of black pepper extract
Saipriya Shettigar, Usha Y. Nayak, Mahalaxmi Rathnanand, Venkatesh Kamath B., Chandrashekar K. S., Vasudev Pai, Aswatha Ram H.N.

Optimization of the formulation of transdermal patches of amiodarone
Ragni Kumari, Virendra Kumar Sharma

Development and validation of RP-HPLC method for quantification of sertraline in nanofiber formulation
Ashok A. Hajare, Girija A. Ghatge, Kiran S. Patil

Elucidating the effect of hesperidin on behavioral and biochemical markers of liver and kidney function in sprague Dawley rats
Pandian Paneer Selvam, Usha Kumari, Dharma Raj Tanimale, Mohamed Asem, Sherly Deborah George, Subramani Parasuraman

Formulation and evaluation of immediate release tablets of zopiclone
Lakshmi Devi Gottemukkula, Rishika Singh, N. Prathyusha, J. Akhila, B. Devender, Ramya Sri. S

Molecular docking studies and In-silico ADMET profile analysis of Triphala plant constituents morin and 9, 10-anthraquinone as potential inhibitors of human estrogen receptor alpha
Satyanarayana Murthy Malladi, Surya Prabha Sadhu, Devendra Kumar Pandey, Nagendra Sastry Yarla

Formulation of microsponge of thyme for acne treatment
Rina G. Maskare, Shital D. Thakre, Akash S. Jaiswal, Darshan S. Chawade, Shirali S. Vishwakarma, Triveni N. Bahekar

The impact of high D-dimer on the clinical outcome of Covid-19 patients at A Private Hospital in Jakarta
Diana Laila Ramatillah, Nona Ainah, Michael, Fauzi Kasim, Purwati, Kashifullah Khan

Stability indicating bioanalytical validation of elexacaftor, ivacaftor and tezacaftor using HPLC in human plasma
S. Marakatham, P. Shanmugapandiyan

Hepato-protective potential of choline and DHA supplements in rats exposed to tobacco particulate matter-A histological study
Jyothsna Patil, Naveen Kumar, Swami Ravindra S, Mohandas Rao KG, Arijit Bishnu, Kiranmai S Rai

Effect of solvents on anti-inflammatory and analgesic activities of leaves extract of Mussa paradisiaca Linn
Poonam Chougule, Prakash Nargatti, Pooja Kothali, Nilesh Chougule

Antifungal activity of Terminalia chebula extract against wilt fungi Fusariumoxysporum an important plant pathogen
Padmalatha A, Dr. Prabha S.B

An integrated molecular docking study of marine bioactive compound as promising drug candidate against SARS CoV-2 receptor in complex with antibody
Avinash Shankar Bhosale, Sagar Dnyaneshwar Sonone, Sachin Madhukar Sonone, H. R. Wagh

Method development and validation of a new stability indicating HPLC and LC-APCI-MS methods for the determination of bumetanide
Dipak Chandrakant Kulkarni, Anima Sunil Dadhich, Mukthinuthalapati Mathrusri Annapurna

Lung and mediastinal tumor core biopsies: Histopathological features of 320 cases
Alyaa Ulaa Dhiya Ul Haq, Etty Hary Kusumastuti, Nila Kurniasari, Isnin Anang Marhana

The growth of ETV6-NTRK3 harbouring cells was inhibited by Artemisia vulgaris L. crude extract
Hoang Thanh Chi, Vo ngoc Tram, Nguyen Trung Quan, Bui Thi Kim Ly

Environmentally friendly analytical methods for quantitative measurement of sofosbuvir in pharmaceutical formulations: Comparison of HPTLC and UV spectrophotometric approaches
Kiran Balasaheb Aher, Girija Balasaheb Bhavar, Madhav Ramdas Shelke1, Sadikali Fakirmahmmad Sayyad

Synthesis, characterization and biological evaluation of some new isoxazole and pyrazole compounds for anti-obesity drug
Bhagyashree Agrawal, Bhaskar Kumar Gupta, Satish Kumar Sahu

Novel chewable gum sticks for the treatment of oral candidiasis
Jaya Agnihotri, Poonam Yadav, Anjali Maurya, Akash Vishwakarma

Synthesis and optimization of nanoparticle chitosan-tripolyphospate Centella asiatica using ionic gelation method with difference sonification time
Bayyinatul Muchtaromah, Eko Budi Minarno, Rahmi Annisa, Arif Nur Muhammad Ansori, Ely Nuril Fajriyah, Prilya Dewi Fitriasari, Listiani Suhargo, Kenji Mishima

Synthesis, characterization and In vitro antimicrobial assessments of a new series benzoimidazoles incorporated quinazoline and thiazine analogues
Ayad Kareem Khan

Formulation development and in vitro evaluation of provesicular gel of ketoprofen for management of Arthritis
Rashmi Madhariya, Alpana Ram

FTIR method for simultaneous determination of captopril and hydrochlorothiazid in raw material and pharmaceutical dosage form
Ali Mhammad, Saleh Trefi, Faten Sliman, Yaser Bitar

Review Article

A systematic review on chemical composition and biological activities of cedar oils and extracts
Oussama Chauiyakh, Elmostafa El Fahime, Samar Aarabi, Oumaima Ninich, Fatiha Bentata, Kamal Kettani, Abdelaziz Chaouch, Aziz Ettahir

Research Articles

New synthetic methods of ureido-substituted benzenesulfonamides as carbonic anhydrase IX inhibitors
Mohammad Hasbi Ghazal, Djamila Ben Hadda, Saleh Trefi, Amir Balash, Mustapha Fawaz Chehna

The immunological response of Salmonella typhi protein subunits (Outer membrane protein 36 kDa, fimbriae 36 kDa, and flagellin) as a candidate for oral typhoid vaccine
Helmy widyastuti, Sanarto Santoso, Sri Winarsih, Sri Poeranto

Preparation, statistical optimization, in-vitro evaluation and characterization of solid lipid nanoparticles of an anti-retroviral drug Nevirapine
R. B. Shinde, A. H. Hosmani, M. A. Shende, R. J. Jarag, Y. S. Thorat

Investigation of the effects of some process variables on the azithromycin microencapsulation by the quasi-emulsion solvent evaporation method
Rawan Alsayad, Antoun Laham

Monocrotaline model of Pulmonary hypertension in immature rats from the perspective of Serotonergic regulation
Diana F. Bilalova, Farida A. Mindubayeva, Razina R. Nigmatullina, Yelena Y. Salikhova

Melt granulation for enhanced dissolution rate and antimicrobial activity of cefpodoxime proxetil
Nouran Abdel Kader, Amal Abo Kamer, Engy Elekhnawy, Mona Arafa, Ebtessam A Essa, Gamal M El Maghraby

European and national measurements of molecular and immunological aspects of diagnosis, prevention, and treatment of coronavirus infection
Galina Rizak, Dmytro Maltsev, Gulshakhar Karkimbayeva, Volodumyr Vivsyannuk, Olena Barabanchyk

Validated RP-UPLC-PDA method for simultaneous estimation of artemether and lumefantrine in API and tablet dosage form
Ashok B. Patel, Shivangi V. Abhangi, Jyotishna B. Choudhary, Amitkumar J. Vyas, Ajay I. Patel, Nilesh K. Patel, Sunny Shah, Devang Sheth

Antibacterial study of the ethanolic extract of local common myrtle leaves Myrtus communis L. (Myrtaceae)
Yazan Islim, Dima Muhammad

The study of the phenolic compounds, antioxidant activity and antibacterial effect of herbal ethanol extracts of Scorzonera purpurea subsp. rosea
Nataliya Stadnytska, Natalija Monka, Nazar Manko, Piotr Pavel Wieczorek, Iza Jasicka-Misiak, Tetiana Holubieva, Vira Lubenets

In situ gelling gastro-retentive raft containing Ficus racemosa fruit extract: A promising approach to treat GERD
Yogesh Shripad Thorat, Prachet Pralhad Bagewadikar, Ganesh Mali, Khalid Konda, Rajesh Bhaskar Nawale, Avinash Hanmant Hosmani

Synthesis and evaluation of amide codrug of ibuprofen and amlodipine for dual inhibition of inflammation and hypertension
Anjali Nayak, Paramita Das, Amit Kumar Das

Review Articles

HPTLC method development of herbal drugs and its validation: An overview
Amber Vyas, Vishal Jain, Umakant Sahu, Narendra Kumar, Neelu Joshi

A review of various analytical methods developed for estimation of paracetamol, diclofenac sodium, and chlorzoxazone in single-component and multi-component dosage form
Lakpa Doma Sherpa, Bibhas Pandit, Bhupendra Shrestha

Mucoadhesive microspheres: An innovative approach to enhance Gastro-retention
Dr. Kamal, Deepika, Neha, Ritu, Shubham

VAR2CSA protein for malaria vaccine or anticancer drug delivery? A review of preclinical and clinical research
Thalib Aditya Hakim, Annissa Retno Arimdayu, Ilma Fauziah Ma’ruf, Wulan Mayasari, Hesti Lina Wiraswati

Insight into ethnopharmacology of quercus infectoria with the possible mechanism of action
Fazil Ahmad, Krishna Mohan Surapaneni, Abeer Mohammed Al-Subaie, Balu Kamaraj

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