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Research Journal of Pharmacy and Technology
Year 2022, Volume-15, Issue-4 (April)
Print ISSN: 0974-3618
Online ISSN: 0974-360X

Table of Contents

Research Articles

Qualitative and quantitative analysis of phytochemicals in some medicinal plants of western himalayas
Manju, Aiman Aziz, Shamee Rehman

Development and evaluation of thermo triggered In situ nasal gel of selegiline for depressive disorders: In vitro, In vivo and Ex vivo characterization
Shiv Kumar Srivastava, Mahesh Prasad, Antesh Kumar Jha

In silico analysis of novel azetidinone substituted benzotriazole and benzimidazole derivatives as Plasmodium falciparum glutamate dehydrogenase inhibitors
Sandip N. Badeliya, Pankaj P. Kapupara, Ankit B. Chaudhary

Multi epitopes potential on surface sars-cov-2 protein as a covid-19 vaccine candidate
Khoirul Anam, Bobi Prabowo, Meike Tiya Kusuma, Yuliati, Sri Winarsih, Tri Yudani Mardining Raras, Sumarno Reto Prawiro

Hypoglycemic activity of methanol fraction of Solanum torvum (swartz) fruits in normal and streptozotocin induced hyperglycemic rat models
Bishwanath Mishra, Durga M. Kar, Laxmidhar Maharana, Sujit Dash, Ganesh P. Mishra

Formulation and evaluation of chronomodulated pulsatile drug delivery system for nocturnal hyperacidity
Rohini Kharwade, Haripriya Nair, Dipali Masurkar, Ajay Pise, Sachin More, Shilpa Pise

Evaluation of anti-oxidant, anti-microbial and phytochemical analysis of different parts of C. bipinatus
Tejaswi Jasti, Manisha Senapathi, Sasank P, Varaprasad Bobbarala, Kandra Prameela

Isolation and identification of antibacterial compound from actinomycetes isolated from mangrove soil
Riya Jalan, Biswaranjan Pradhan, Santosh Kumar Singh, Anuradha Das, Rajib Lochan Barik, Jyotisikha Meher, Rashmi Ranjan Mishra, Debasmita Dubey, Bikash Chandra Behera

A validated ultra performance liquid chromatography method for simultaneous estimation of diacerein and aceclofenac in bulk and pharmaceutical formulation
Bharatee P. Chaudhari, Kratika Daniel

Box behnken design for optimization of mirabegron solid dispersion by fluidized bed processing
Rajendra K. Surawase, Kamalkishor G. Baheti

In-silico ligand and structure based design of hiv-1 protease inhibitors: Current trends and future directions
S. Ramasamy, Sushmita Gupta, Ritu Rani Chaudhary, Amit Kumar Verma

Analysis of adverse drug reactions associated with anti-tubercular drugs - A retrospective study
Dharini Boopathi, Akshatha J S, Uma Buggi, Hema Siva, Arun K P, Deepalakshmi Mani

Biological activities of steroids and extracts from xestospongia sp. growing in southeast Sulawesi (Indonesia)
Baru Sadarun, Wahyuni, Muhammad Hajrul Malaka, Adryan Fristiohady, Agung Wibawa Mahatma Yodha, Nur Syifa Rahmatika, Zulfikri Saleh Islami, Muhammad Nurjayadin, Carla Wulandari Sabandar, Ahmad Darmawan, Andini Sundowo, Andi Rifky Rosandi, Sahidin I

Comparison of diagnostic tests for detection of nonstructural-1(NS1) antigen dengue virus using immunochromatography and fluorescence immunoassay methods
Nelly Zuroidah, May Fanny Tanzilia, I Gusti Agung Ayu Eka Putri Sunari, Billy Jordan Wrahatnala, Faradila Khoirun Nisa Haki, Aryati, Puspa Wardhani, Dominicus Husada, Ali Rohman, Siti Nadia Tarmizi

Spectroscopic method for the quantification of residue of tetramethylthionine chloride on swab from manufacturing equipment in support of cleaning validation
Kishan Malviya, Monika Maheshwari, Mahendra Singh Rathore

The hypoglycemic and hypolipidemic effect of 5- naphthalidin-2, 4 thiazolidinedione derivatives in alloxan induced type ii diabetic model
Rekha S, Kalpana Divekar, Chandrashekhara S

Preliminary phytochemical analysis on the leaves extracts of Sida acuta burm. f. and Sida rhombifolia linn. family malvaceae
S. Selvadurai, P. Shanmugapandiyan

Effect of vitamin d supplementation in patients with cardiometabolic disorders- A clinical study in ahmedabad population
Debdoot Basu, Anant Yadav, Anita A. Mehta

Gc-ms analysis of phytochemicals and green synthesis of silver nanoparticles from Amaranthus parganensis
Smarika Chauhan, Swamynathan G

Approaches to ensure comparability of the results of assessment of customer loyalty to a pharmacy
Olena Piven, Elena Shuvanova, Irina Tkachenko, Aleksandr Xrenov

Effect of antenatal betamethasone on respiratory distress syndrome in preterm neonates
Haripriya P. S., Dhanya Mary Louis, Nikita Naushad, Merin Tomy, Sreelakshmi M.S., Narmadha M.P.

Synthesis and characterization of mixed ligand complexes from curcumin and new schiff base derived from isatin for some metallic ions and evaluation biological activities
Shaimaa Ahmad Hassan

Antioxidant and antibacterial potential of Lycium shawii roem. and schult (AWSAJ) and Tetraena qatarensis (HADIDI) beier and thulin leaves: A herbal approach to combat drug resistance and oxidative stress
Mashael W. Alruways, Nazam Khan

Flaxseed mucilage hydrogel based floating drug delivery system: Design and evaluation
Shreya Ramteke, Naresh Haigune, Sachin More, Shilpa Pise, Ajay Pise, Rohini Kharwade

Digitalization of pharmaceutical business in Ukraine
Timanyuk Iryna, Bondarieva Iryna, Malyi Volodymyr

Effect of anti-inflammatory activity of aqueous, hydro-ethanol and methanol extracts of two unani formulations
Lahari Kuna, Shravan Kumar Ghali, Towseef Amin Rafeeqi , Gulam Mohammed Husain, Mohammed Abdul Waheed, Ghazala Javed, Munawwar Husain Kazmi, Alokananda Chakraborty

Effect of natural/ synthetic polymers and super disintegrants on the formulation of zafirlukast fast dissolving film
Ashti M. H. Saeed, Maryam Alaayedi, Hayder Yahya Mansoor Al-Jarsha

Lower back pain classification using parameter tuning
Sushmita Lenka, Nancy Victor

In vitro antiplatelet activities of aqueous extract of garlic (allium sativum) and black garlic in human blood
Lia Agustina, Emilia Gan, Ninis Yuliati, Giftania W. Sudjarwo

Evaluation of N - butanol fraction of Albizia procera (roxb.) benth against diabetes mellitus with rats
D. Anand, M. Sathish

Formulation, development and release enhancement of sustained release tablet of antidiabetic drug glipizide by the use of natural polymers
Sonia Chauhan, Rupa Mazumder, Rakhi Mishra, Avijit Mazumder, Nidhi Srivastava

A comparative study on ecg changes among normal and otherwise healthy congenitally deaf children
Suma. S, Hari Prasad. V, Abeetha. S, Tejashwini. K, Renu Sharda

Cost-effectiveness analysis of afatinib versus gefitinib in non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutation in Indonesia: Observational studies with retrospectives
Seftika Sari, Tri Murti Andayani, Dwi Endarti, Kartika Widayati

A novel co-crystallization technique to enhance the physicochemical property of bcs class-ii drugs using efavirenz as a model drug
Vikram R. Shinde, Yogesh V. Pore, J. Venkateshwara Rao

Growth dynamics following growth hormone treatment in group of iraqi patients with turner’s syndrome
Muneer Fadhil Ridha

Protective effect of the combination of hydroalcoholic extracts of Asparagus racemosus, centella asiatica, plumeria rubra with glibenclamide in experimentally induced diabetic nephropathy in rats
Amruta Vidyadhar Yadav, Chandrashekhar Devidas Upasani

Acceptance of problem-based learning by preclinical students from a public university and its impact on their learning
Khin Than Yee, Helmy Bin Hazmi, Tin Moe Nwe, Mya Mya Thwin, Mon Mon Yee, Mi Mi khaing, Soe Lwin, Myat San Yi

In vitro evaluation of antibacterial, antioxidant, and anticancer properties of panchagavya
Sivaji Sathiyaraj, Gunasekaran Suriyakala, Arumugam Dhanesh Gandhi, Thirumalpur Neelakandan Baskaran, Ranganathan Babujanarthanam

Expression level of HSP70 and COX-2 in breast cancer proliferation in Dr. Soetomo general hospital, Surabaya, Indonesia
Rebecca Agustine Kristian, Willy Sandhika, Heriyawati

Effect of naringin co-administration on oral bioavailability of efavirenz in rabbit
Mohammad Asif, Rakesh K. Patel, Hardik Patel, Sadaf Jamal Gilani

New approach for determination of phenylephrine hcl in pure and pharmaceutical formulation using a various microextraction methods
Nagham K. Kareem, Mohammed Z. Thani, Khalid F. Al-Rawi

Current clinical anticipation of arbidol against covid-19: Possibilities
Ramana Hechhu, Rangapuram Vasanthi, Tamrat Balcha Balla, Kaliaperumal J

Coumarins as potential anticoagulant agents
Abhishek Kumar, Pankaj Kumar, Shravya H, Aravind Pai

Characterization and synthesis of milk thistle nanoparticles to overcome oxidative stress induce testicular damage in male rats
Essa Daham Jalloob, Rusul Heider, Abdulamir A. Al Zahid, Iman Jawad Jaber, Adnan Mansour Jasim, Mohsin, Rawaa, Kareem, Ameer Ridha Dirwal, Dheyaa Ali Neamah

In- vitro antiurolithiatic potential of leaves of Anneslea fragrans wall. against calcium oxalate kidney stones and its ft- ir analysis
Suresh Kumar

Rapid quantitative estimation of glipizide and sitagliptin in rat plasma by liquid chromatography and mass spectroscopy (LC-MS)
A. Anka Rao, K. Pavan Kumar, A. Narayana Rao, Narender Malothu, B. Prassana Kumar Desu, Naga Raju Bandaru

Method development and validation of simultaneous determination of assay of quinapril and tolcapone
O.S.S. Chandana

Microbiological profile with antibiotic sensitivity pattern for chronic suppurative otitis media in a Tertiary Hospital, Indonesia
Artono, Rahmi Surayya, Nyilo Purnami, Edi Handoko

3d qsar analysis of flavones as antidiabetic agents
Navin Sainy, Nidhi Dubey, Rajesh Sharma, Nitin Dubey, Jitendra Sainy

A validated stability indicating rp-hplc method for simultaneous determination of lopinavir and ritonavir in bulk and tablet dosage form
Prasanthi, Dannana Gowri Sankar

Factors associated with glycemic control among syrian patients with type 2 diabetes mellitus
Khadija Khalil, Afraa Zrieki

Applications of fourier transform infrared and uv-visible spectroscopy for the demonstrating sameness of ganirelix peptide in liquid injection formulation
Kumarswamy Ummiti, J.V. Shanmukha Kumar

Transanethole protects against global cerebral ischemia through its anti-inflammatory and anti apoptotic activity
Hima Saila M, Santhrani Thakur

Phytochemistry and cytotoxicity analysis of kemang (mangifera kemanga) fruit extract on hela cervical cancer cell line
Prajnadiyan Catrawardhana, Ersal Rasyid Saharso, Yusuf Mushlih, Yatri Hapsari, Fadilah Fadilah

Preparation, evaluation and development celecoxib prolonged release (PR) tablets by using cellulose polyacrylic acid - based polymers
Svetlana Suslina, Ahmed Alkhodri

A desirability approach for antidiabetic and antiinflammatory efficacy of Ficus subincisa bark
A. Shukla, P. Pokhriyal

The roles of insulin growth factors-1 (IGF-1) in bone graft to increase osteogenesis
Chiquita Prahasanti, Sonny Perdana

Synthesis, and antimicrobial evaluation of new hydrazone derivatives of (2,4-dinitrophenyl) hydrazine
Halah A. Sahib, Mohammed K. Hadi, Maadh Qusay Abdulkadir

In vitro antioxidant and anticholinesterase activities of extracts from the leaves of Cassia moschata kunth
Suciati Suciati, Wachidatur Rizqiyah, Dwiki Nur Inayah, Retno Widyowati, Wiwied Ekasari, Nungruthai Suphrom

Chemical composition and evaluation of the antibacterial and antifungal activities of pre-rif Teucriumpolium essential oil
Oussama Chauiyakh, Aziz Et-Tahir, Badr Satrani, Mohamed Ghanmi, Sara Cherrad, Kamal Kettani, Abdelaziz Chaouch, Malika Tiskar

Development and validation of rp-hplc method for the determination of ropinirole hydrochloride in bulk and pharmaceutical dosage forms
Sowjanya Gummadi, Durga S. Siyyadri

The risk of genetic polymorphisms in the immune genes on the developed of respiratory allergic diseases
Israa Hussein Hamzah, Noor Al-Huda Ali A. H. Saeed, Alaa N Mohammed Ali

The effect of the application of topical shallots on infant pain post-immunization
Zainab

Significance of kuttana in the preparation of Guggulu vati processed in Triphala kwatha
Arun N., Vinaykumar R. Kadibagil

Hysteroscopic procedure as day care cases under tiva with dexmedetomidine vs ketamine
Jayashree Sen, Bitan Sen

Development and validation of rp-hplc method for the estimation of alogliptin in api and tablet formulation
Suyash Ingle, Varsha Tegeli, Avinash Birajdar, Gajanand Nangare

Mechanism of apoptosis retinal ganglion cells Rattus norvegicus caused by ethambutol
Lukisiari Agustini, Nurwasis, Aryati, Gatut Suhendro, Winarto, I Ketut Sudiana, Widjiati, Bambang Purwanto

Development of new analytical method for the estimation of raltegravir in rabbit plasma
Deepthi Sandhala, Srinivas Lankalapalli

Preliminary phytochemical screening and infra-radiation test of crude the leaves of nothophanax scutellarium merr., Moringa oleifera and PiperBetle L.
Cut Sriyanti, Tongku Nizwan Siregar, Mudatsir, Azhari Gani

Synthesis and antimicrobial evaluation of some novel 1,5 benzodiazepine derivatives derived from pyrrolyl chalcones
Pankaj Kumar, Abhishek Kumar, Jean Sandra Pinto, Sachin A. Kumbar, Nanditha Bhat, Prashant Nayak

Analysis of phytochemical compounds present in some traditional anti-dermatophytic plants by thin layer, column chromatographic methods
Sownthariya C., Shanthi P., Balavinayagamani Ganapathy, Priyadharshni K., Thiripura Sundari U., Nagaraja Suryadevara

Physico-chemical studies of ground water quality of chirawa, buhana and surajgarh tehsil of Jhunjhunu district. Rajasthan (with special re ference to fluoride)
Anita Kumari, Y.K. Gupta

Acute oral toxicity of essential oil extracted from the leaves of Ocimum sanctum L. (Thulasi) in female wistar albino rats
Venugopal Jayapal, V. Subha, K. Bhavani, Kartik Janardan Salwe, K. Manimekalai, Josh M Easow, Stephen Selvaraj

Effect of pelvic floor muscle training with biofeedback on stress urinary incontinence in females, Kelantan, Malaysia: A pilot study
Nur Yanti Hariana Bt Othman, Naresh Bhaskar Raj, Naing NN, Mahadeva Rao US, Enie Akhtar, Lee Wan Zhen, Anuar Md Zain

Standardization, determination of antioxidant activity and total flavonoid contents of purified extract of Lawsonia inermis leaves
Mus Ifaya, Ahmad Muhtadi, Ida Musfiroh, I Sahidin, Amar Ma'ruf, Syawal Abdurrahman

In-vitro antioxidant activity of Oxalis carniculata linn and investigation of plausible mechanism of photo-protection by molecular modeling study
Madhuri Baghel, Hemant Badwaik, Sangeeta Patil

Review Articles

Role of duloxetine in neuropathic pain: A clinical impact, mechanism, challenges in formulation development to safety concern
Linu Dash, Bimlesh Kumar, Anupriya, Varimadugu Bhanukirankumar Reddy, Indu Melkani, Narendra Kumar Pandey, Kardam Joshi, Dhara Patel

Utilization of polymethyl methacrylate and hydroxyapatite composite as biomaterial candidate for porous trabecular dental implant fixture development: A narrative review
Chiquita Prahasanti, Darmawan Setijanto, Diah Savitri Ernawati, Rini Devijanti Ridwan, David Buntoro, Kamadjaja, Anita Yuliati, Asti Meizarini, Nike Hendrijantini, Agung Krismariono, Shafira Kurnia Supandi, Tania Saskianti, Ratri Maya Sitalaksmi, Djoko Kuswanto, Tansza Setiana Putri, Nastiti Faradilla Ramadhani, Muhammad Dimas Adiya Ari, Alexander Patera Nugraha

Role of the nlrp3 inflammasome in periodontal disease: A tour d'horizon
Pradeep Koppolu, Rasheed Abdulsalam

Zoonosis and bats: Evolution of virulence and disease outbreaks
Ankita Sahu, Vinit Singh Baghel

Applications of microbial bioflocculants for environmental remediation: An overview
Nilanjana Das, Ashwini Prabhakar Shende, Keerthana G, Sanjeeb Kumar Mandal

Polyherbal formulation for primary dysmenorrhea: A review
Choo Shiuan Por, Mogana R., Gabriel A. Akowuah, Sasikala Chinnappan, Nor Hayati Abdullah

Biological screening and structure activity relationship of benzothiazole
Khyati Bhagdev, Sibaji Sarkar

Influence of dietary molecules on human health: Whey proteins
Kumari Rashmi, Mehak Gupta, Shreyoshi Tarapdar, Megha Duggal, Shubham Tyagi, Harmanpreet Kaur, Priyank Vyas, Amit Gupta

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