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Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 7
First page : ( 3504) Last page : ( 3508)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.00607

Evaluation of cytotoxicity of normal vero and anticancer activity of human breast cancer cell lines by aqueous unripe fruit extract of Solanum torvum

Shanthi D., Saravanan R.*

Post Graduate and Research Department of Zoology, Dr Ambedkar Government Arts College, Vyasarpadi, Chennai600039, Tamil Nadu

*Corresponding Author E-mail: rsaravanan51283@yahoo.com

Online published on 25 August, 2021.

Abstract

In the present study aqueous extract of Solanum torvum unripe fruits was used to evaluate its cytotoxic effect and anticancer activity through in vitro studies by 3-(4, 5 dimethyl thiazole-2-yl)-2, 5-diphenyl tetrazolium bromide-MTT assay) on Normal VERO cell line and MCF-7 (Human breast adenocarcinoma cell line). Aqueous extracts of Solanum torvum unripe fruits was found to be effective in the prevention of cell proliferation by breast adenocarcinoma cell lines at 1000 μg/ml from the results obtained during 24 hours of incubation.

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Keywords

Unripe fruits of Solanum torvum, Normal VERO cell line, MCF-7 (Human breast adenocarcinoma cell line), MTT assay.

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