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Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 4
First page : ( 2004) Last page : ( 2008)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.00355

Evaluation of anti-inflammatory and anti-arthritic activity of Luffa acutangula peel extract mediated ZnO nanoparticles

Ananthalakshmi R.1*, Rathinam S. R. Xavier Raja2, Sadiq A. Mohamed3

1Biochemistry Division, National Sugar Institute, Kanpur, Uttar Pradesh, India

2Department of Chemistry, Sacred Heart College, Tirupattur, Vellore District, Tamilnadu, India

3Department of Biochemistry, APCAS, Kalavai, Vellore District, Tamilnadu, India

*Corresponding Author E-mail: ananthuknocks@gmail.com

Online published on 3 June, 2021.

Abstract

The special improved characteristics and different application of zinc oxide nanoparticles made them to play a major role among metal oxide nanoparticles. Zinc oxide nanoparticles were successfully synthesized in a cost effective, time saving and safety method using Luffa acutangula peel extract. Zinc oxide nanoparticles showed maximum absorption peak at 377.77nm in UV visible absorption spectroscopic studies. The fourier transform infrared spectroscopy (FTIR) studies revealed the presence of various functional groups attributed by aqueous peel extract along with the zinc oxide nanoparticles. The shape of the zinc oxide nanoparticles was found to be spherical under scanning electron microscopy and they were found to be agglomerated. The zinc oxide nanoparticles prepared using Luffa acutangula showed anti-inflammatory activity when studied by Human RBC membrane stabilization method. Also they effectively inhibited the egg albumin and bovine serum albumin denaturation by which they are confirmed to have anti-arthritic activity.

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Keywords

Zinc oxide nanoparticles, Luffa acutangula, Characterization, Anti-inflammatory and Anti-arthritic.

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