Evaluation of anti-inflammatory and anti-arthritic activity of Luffa acutangula peel extract mediated ZnO nanoparticles Ananthalakshmi R.1*, Rathinam S. R. Xavier Raja2, Sadiq A. Mohamed3 1Biochemistry Division, National Sugar Institute, Kanpur, Uttar Pradesh, India 2Department of Chemistry, Sacred Heart College, Tirupattur, Vellore District, Tamilnadu, India 3Department of Biochemistry, APCAS, Kalavai, Vellore District, Tamilnadu, India *Corresponding Author E-mail: ananthuknocks@gmail.com
Online published on 3 June, 2021. Abstract The special improved characteristics and different application of zinc oxide nanoparticles made them to play a major role among metal oxide nanoparticles. Zinc oxide nanoparticles were successfully synthesized in a cost effective, time saving and safety method using Luffa acutangula peel extract. Zinc oxide nanoparticles showed maximum absorption peak at 377.77nm in UV visible absorption spectroscopic studies. The fourier transform infrared spectroscopy (FTIR) studies revealed the presence of various functional groups attributed by aqueous peel extract along with the zinc oxide nanoparticles. The shape of the zinc oxide nanoparticles was found to be spherical under scanning electron microscopy and they were found to be agglomerated. The zinc oxide nanoparticles prepared using Luffa acutangula showed anti-inflammatory activity when studied by Human RBC membrane stabilization method. Also they effectively inhibited the egg albumin and bovine serum albumin denaturation by which they are confirmed to have anti-arthritic activity. Top Keywords Zinc oxide nanoparticles, Luffa acutangula, Characterization, Anti-inflammatory and Anti-arthritic. Top |