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Year : 2021, Volume : 14, Issue : 2
First page : ( 1091) Last page : ( 1093)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00196.7

Prophylactic antibiotics and prevention of surgical site infections

Satishchandra Aithamraju*1, Anusha R.1, Krishna E. Vamshi1, Eshwaraiah Chinna2

1Department of Pharmacology, Anurag Pharmacy College, Ananthagiri, Kodad, Telangana.

2Department of Pharmacognosy, Anurag Pharmacy College, Ananthagiri, Kodad, Telangana.

*Corresponding Author E-mail: satishchandrano.1@gmail.com

Online published on 30 April, 2021.


The aim of antimicrobial prophylaxis should be safety and cost effectively reduce the incidence of infections in cases in which surgery may lead to contamination of normally sterile areas or in which infection is unlikely but may cause major morbidity. Topical and parentral antibiotic prophylaxis after surgery is defined as the use of these antibiotic to prevent infection at surgical site to sterile the body after surgery by preventing systemic infections. The antibiotic selected should only cover the likely pathogens. It should be given at the correct time. A single dose of antibiotic is usually sufficient if the duration of surgery is 4 hours or less. Inappropriate use of antibiotics for surgical prophylaxis increases both cost and the selective pressure favouring the emergence of resistant bacteria.



Surgical prophylaxis, Morbidity, Antibiotic.


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