(35.172.224.102)
Users online: 1529    [ij] [ij] [ij] 
Email id
 

RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 2
First page : ( 977) Last page : ( 980)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00174.8

Effect of Allium sativum on dental plaque pH-A double blinded randomized parallel placebo-controlled trial

Anu V.1, Saraswathi P.2, Sangeetha R.2, Savitha K. M.2, Swetha P.2

1MDS, Associate Professor and Head, Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Jeppiar Nagar, OMR, Chennai, Tamil Nadu-603103.

2Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Jeppiar Nagar, OMR, Chennai, Tamil Nadu.

*Corresponding Author E-mail: pcnanu@gmail.com

Online published on 30 April, 2021.

Abstract

Background: This study was aimed to assess the antibacterial effect of garlic extract against human dental plaque pH. The hypothesis of this study is that the use of mouthwashes incorporated with allicin may resist the decrease in the plaque pH and thus prevent dental caries. Materials and methods: A double blinded randomized control study was conducted among 90 participants. The study participants were then divided randomly into 3 groups by the chief investigator each group comprising of 30 participants: Group 1: allicin extract, Group 2: chlorhexidine mouthwash and Group 3: combination of both. The plaque collected was diluted in 20ml of distilled water and baseline pH was estimated using a digital pH meter. The participants were asked to swish and spit by using the mouthwashes. The plaque was collected and then mixed with 20ml of distilled water and the pH was estimated. This procedure was repeated at regular five minute interval for half an hour. ANOVA and Bonferroni post hoc test was used for analysis. Results: All 3 study groups showed a significant difference within group from baseline to 30 minutes. Intergroup comparison showed that the mean value of combination group was found to be higher when compared to other groups. Conclusion: Garlic mouth wash is effective against dental plaque pH. However, the results were best obtained when used in combination with chlorhexidine.

Top

Keywords

Allicin, Garlic, Dental plaque, Dental caries, Periodontal disease.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
598,390,720 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.