Users online: 1848    [ij] [ij] [ij] 
Email id

Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 12
First page : ( 6405) Last page : ( 6408)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.01107

Antitubercular study on stem bark of Albizia procera (ROXB.) BENTH using Microplate Alamar Blue assay (MABA)

Sathish M.*, Anand D., Guruvigneshwari M., Kumaar Dhiraj S., Soundarya S., Nijanthan S.

Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai3

*Corresponding Author E-mail: sathishpharmacy14@gmail.com

Online Published on 02 March, 2022.


Albizia procera commonly known as white siris is a large deciduous tree of the family Mimosideae, widely distributed throughout India. Traditionally the plant is used in convulsions, pain, delirium, cancer and septicemia. The decoction of bark is given for rheumatism, hemorrhage and is considered useful in treating pregnancy problems, for stomach ache and sinus.The preliminary phytochemical screening of ethanol extract of Albizia procera shows the presence of active constituents like flavonoids, phenolic compounds and tannins. Earlier studies show the flavonoids and phenolic compounds play major role in antitubercular activity. Based on this, we made an attempt to evaluate the antitubercular potential of this plant. The ethanolic extract and its fractions (Hexane and Ethyl acetate) were investigated for antitubercular activity using Alamar Blue dye method (MABA), in which Mycobacterium tuberculosis was sensitive upto 3.12 g/ml.The extract and fractions show better anti tubercular activity than streptomycin and potentially equal to pyrazinamide and ciprofloxacin. The observed activity may be due to the presence of flavonoids and phenolic compound which is confirmed by HPTLC. This investigation on stem bark of Albizia procera has the potential to be developed further into a natural Anti-TB drug.



Flavonoids, Antitubercular, Albizia procera, Pyrazinamide, Ethyl acetate.


║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
623,076,705 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.