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Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 12
First page : ( 6207) Last page : ( 6210)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.01074

A flavonoid compound of Turbinaria decurrens Bory with The potential antioxidant and anticancer activity

Sami Fitriyanti Jumaetri12*, Soekamto Nunuk Hariani1, Okino Tatsufumi3, Firdaus1, Latip Jalifah4

1Department of Chemistry, Hasanuddin University, Indonesia

2Sekolah Tinggi Ilmu Farmasi Makassar, Indonesia

3Faculty of Environmental Earth Science, Hokkaido University, Japan

4School of Chemical Sciences and Food Technology, Universiti Kebangsaan Malaysia, Selangor

*Corresponding Author E-mail: nunukhariani@unhas.ac.id

Online Published on 02 March, 2022.

Abstract

Isolation and characterization of quercetin flavonoid compound from Dutungan Island, South Sulawesi Province, Indonesia has been successfully done from ethyl acetate extract. Extraction method used maceration, isolation used chromatography, anticancer activity with MTT method and antioxidant test used DPPH radical. Structure was discussed with the FT-IR, NMR spectrophotometer and compared with the literature. Total flavonoids from ethyl acetate extract were 4.8 mgEQ/g, IC50 value of antioxidant activity was 4.23 g/ml using the DPPH method (2, 2-diphenyl-1-picrylhydrazyl), and anticancer activity of H460 cells IC50 value was 10.95 g/ml. The quercetin compound is potential as an anticancer and was first report in the T. decurrens Bory species.

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Keywords

Turbinaria decurrens Bory, Antioxidant, Quercetin, Anticancer, Total flavonoids.

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