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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 471) Last page : ( 476)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00086.X

Herbosomes: Impressive tool for better bioavailability and bioactivity of plant extracts and botanicals

Nautiyal Vinod1, Roy Amit1*, Sahu Ram Kumar2, Fattepur Santosh3

1Columbia Institute of Pharmacy, Raipur, Chhattisgarh, India.

2Department of Pharmaceutical Science, Assam University (A Central University), Silchar, Assam, India.

3School of Pharmacy, Management and Science University, Seksyen 13, 40100, Shah Alam, Selangor, Malaysia.

*Corresponding Author E-mail wakratund@gmail.com

Online published on 22 April, 2021.

Abstract

Herbosomes are the minute structures in which standardized herbal extract are incorporated into a phospholipid, resulting to a lipid friendly complex which is also called phytosomes. The potent phytoconstituents are incorporated within a phospholipid complex which is well absorbed by the lipid rich cell membrane system, thus bioavailability of the poorly absorbed polar phytoconstituents are enhanced. These herbosomes may be prepared by various methods like lyophilization technique, salting out process, solvent evaporation etc. The Visualization, vesical size, zeta potential, entrapment efficiency, transition temperature, surface tension measurement, vesicle stability and drug content are used for evaluation of Herbosomes. Herbosome are becoming more popular day by day because of their specificity selectivity and improved bioavailability. Laying down the absorption problem with traditional herbal extracts and other dosage form herbosomes are the complexes with enhanced bioavailabilty and potency. The herbosome of the silymarin, curcumin, sinigrindiomisin are successfully prepared and are available to the market. Thus it is clear that the herbosomes are the novel preparation for the complex natured herbal constituents for the better bioavailability and selectivity and maintaining the potency. This paper highlighted about advanced technology, preparation, properties, advantages, merits, demerits, characterization techniques, in vivo evaluation, application and marketed formulation of Herbosomes.

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Keywords

Herbosomes, Phospholipid complex, Characterization techniques, Marketed formulation.

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