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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 437) Last page : ( 441)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00079.2

Assessment of pharmacognostic parameters and antioxidant potential of bitter melon or karela (Momordica charantia L.) fruits by DPPH method

Sharma Gaurav Kumar*, Sharma Sarita, Chasta Pankaj, Joshi Rishi Kumar, Tiwari Atul, Chandrul Kaushal K.

Department of Pharmacy, Mewar University, Gangrar-312901, Dist-Chittorgarh, Rajasthan, India

*Corresponding Author E-mail: garvsharma2050@gmail.com

Online published on 22 April, 2021.

Abstract

The aim of the present study was to investigate the different pharmacognostic parameters and to evaluate the antioxidant activity of the fruits of Momordica charantia L. by the DPPH method. Aqueous, ethanol, petroleum ether and chloroform extracts of the Momordica charantia L. fruits were prepared and subjected to determine physical constants and phytochemical screening (Qualitative Chemical Tests), which revealed the details of loss on drying, ash values, extractive values, fluorescence analysis and presence of phytoconstituents such as carbohydrates, proteins, steroids, terpenoids, glycosides, flavonoids, and lipids. The antioxidant activity of the Momordica charantia L. fruit extracts was also determined by the DPPH method using ascorbic acid as standard. The results obtained in this study support the use of Momordica charantia L. in herbal medicine and it can be used as a potent antioxidant in the treatment of many diseases resulting from more reactive oxygen species (ROS) presence.

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Keywords

Herbal medicine, Momordica charantia L., Antioxidant, Ascorbic acid DPPH, ROS.

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