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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 369) Last page : ( 372)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00067.6

In vitro antilithiatic study of ethanolic extract of roots of Ipomoea digitata Linn

Namdeo Kamta Prasad*, Naskar Sumanta, Beck Neeli Rose

SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur,, Chhattisgarh, India.

*Corresponding Author E-mail drkpnamdeo@gmail.com

Online published on 22 April, 2021.

Abstract

The main objective of this study was to evaluate in vitro antilithiatic activity of ethanolic extract of roots of Ipomoea digitata Linn. Inhibitory effect of extract on in vitro crystallization was analysed by nucleation assay. Cystone tablet a marketed drug used as a standard drug which is dispersed into 100ml buffer solution for compare of various concentration of ethanolic root extract of Ipomoea digitata Linn. The inhibitory activity of root extract on the nucleation of calcium oxalate crystals and the rate of aggregation in calcium oxalate crystals was determined by spectrophotometric assay. Investigation revealed that ethanolic extract of roots of Ipomoea digitata Linn is positive effect on inhibition for formatting precipitation of calcium and potassium in vitro.

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Keywords

Antilithiatic, Ipomoea digitata Linn, Urolithiasis, Calcium oxalate, Aggregation.

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