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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 331) Last page : ( 336)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00061.5

Evaluation of Antibacterial and Antioxidant activities of Tribulus terrestris L. Fruits

Abdulqawi Latifa Nasser A.1*, Quadri Syed Atheruddin2

1Department of Zoology, Maulana Azad Collage, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India.

2Department of Zoology, Maulana Azad Collage, Dr. Rafiq Zakaria Campus, Aurangabad, India.

*Corresponding Author E-mail: latifaabdulqawi@gmail.com

Online published on 22 April, 2021.

Abstract

The present study comprises screening some phytochemical compounds, antimicrobial activity and antioxidant activity in methanolic and aqueous extracts of Tribulus terrestris L fruits. The phytochemical analysis revealed the presence of alkaloids, Tannins, Glycosides, Flavonoids, Saponins, and Phenols. A well-diffusion method determined the antibacterial effect of T. terrestris extracts against both Gram-positive (Staphylococcus auras and Methicillin-resistant Staphylococcus aureus ATCC43300 (MRSA), and Gram-negative bacteria Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, and Escherichia coli ATCC25922. The methanolic extract was the most active extract against tested bacteria with a minimal inhibitory concentration (MIC) value of 6.25mg/ml. An antioxidant activity using DPPH assay showed that IC50 of methanolic and aqueous extracts were 3.94μg/ml and 22.45μg/ml, respectively).

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Keywords

Tribulus terrestris, Phytochemical, Antibacterial, Antioxidant.

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