(34.231.21.105)
Users online: 1223    [ij] [ij] [ij] 
Email id
 

RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 254) Last page : ( 258)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00045.7

The effect of antihypertensive herb formula of Indonesian traditional medicines against serum uric acid levels in mild Hypertensive patients

Nisa Ulfatun1*, Astana Peristiwan R Widhi1, Kuncoro Hadi2

1Traditional Plant and Traditional Medicine Research and Development, Ministry of Health Republic of Indonesia, National Institute Health Research and Development.

2Faculty of Pharmacy, University of Mulawarman, Samarinda, Indonesia.

*Corresponding Author E-mail: redfa01@gmail.com

Online published on 22 April, 2021.

Abstract

The objective of the study was to determine the effect of herb formula consisting of Syzygium polianthum leaves, Centella asiatica leaves, Imperata cylindrica roots, Myristica fragrans seeds, Curcuma xanthorizza rhizomes, Curcuma longa rhizomes and Phyllanthus niruri herbson serum uric acid levels of patients with mild hypertension. This research method was a quasi-experimental study with pre-post control design, noncomparative, conducted at clinical of saintification of jamu Hortus Medicus over 8 weeks. As much as 60 volunteers-fulfilling the inclusion and exclusion criteria were recruited as subjects. Serum uric acid level, renal and liver function were calculated at baseline, middle and end of study (at the end 8 weeks). There was a statistically significant difference between mean serum uric acid level at baseline and the end of treatment on mild hypertensive patients with hyperuricemic, which had a p-value < 0.05 (p = 0.023 (CI 95% 0.15–1.64)). Nevertheless. the number of subjects with hyperuricemia increased from 21.6% to 23.3%. at day 56. This study concludes that the antihypertensive formula is more favorable in lowering serum uric acid levels in mild hypertensive patients which had hyperuricemia.

Top

Keywords

Indonesian traditional medicines, Herb formula, Mild hypertension, Uric acid.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
596,792,921 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.