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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 167) Last page : ( 170)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00029.9

Formulation and Evaluation of herbal cream for treating psoriasis

Iriventi Padmini*, Gupta N. Vishal

Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagara, Mysuru, Sri Shivarathreeshwara Nagara, Mysuru-570015, Karnataka, India.

*Corresponding Author E-mail: paddhu.iriventi@gmail.com

Online published on 22 April, 2021.

Abstract

Psoriasis is the most common chronic autoimmune disease. The objective of the present study was to formulate herbal cream that consists of Azadirachta indica (Neem) extract used in treating Psoriasis. Various phytochemical identification tests were carried out using reagents. DPPH (2, 2-diphenyl-1-picrylhydrazyl) free radical scavenging assay was carried out to confirm antioxidant activity. Coconut oil, Olive oil and Vitamin E oil were used in the formulation which provides different pharmaceutical activities. Phytoconstituents present in the herbal extract were identified by Liquid Chromatography-Mass Spectroscopy (LC-MS) studies. Evaluation studies were carried out for prepared cream. LC-MS studies concluded that various herbal constituents were identified and it concludes that active constituents responsible for treating psoriasis were present in the obtained extract and also possessed antioxidant activity.

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Keywords

Azadirachta indica, Psoriasis, LC-MS, Phytochemicals, Antioxidant activity.

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