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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 115) Last page : ( 121)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00021.4

Analysis methods for medications improving cerebral circulation

Pashanova Olga V.1*, Ermakov Dmitriy A.2, Philippova Alla V.3, Tikhonova Yuliya A.4, Pronkin Nikolay N.5

1Department of Economics and Organization of Pharmacy, I.M. Sechenov First State Medical University, Moscow, Russian Federation

2Department of Pharmacy, I.M. Sechenov First State Medical University, Moscow, Russian Federation

3Department of Biology and General Genetics, I.M. Sechenov First State Medical University, Moscow, Russian Federation.

4Department of Organization and Economics of Pharmacy, I.M. Sechenov First State Medical University, Moscow, Russian Federation

5Department of Medical Computer Science and Statistics, I.M. Sechenov First State Medical University, Moscow, Russian Federation

*Corresponding Author E-mail: ov_pashanova@rambler.ru

Online published on 22 April, 2021.

Abstract

The objective of the study was to evaluate the efficacy of medical treatment in patients diagnosed with acute cerebrovascular accident (ACVA) included in the REGION inventory. The research was carried out in 2019 in 4 municipal primary health-care facilities in Moscow (Russia) and included the processing of past medical histories in two groups of totally 750 patients. Group I involved 400 patients treated against ACVA before 2017, and Group II comprised 350 patients treated from 2017 to 2019 inclusive. Patients of both groups were compared across the frequency of medications prescription before admission to the clinic with ACVA diagnosis, during outpatient treatment up to six months, and after discharge. Comparative analysis was performed based on telephone surveys and applying the Morisky Green medications adherence assessment scale. Before admission to the clinic, patients from the second group compared to those from the first one was 2.9 times more frequently prescribed with statins (p ≤ 0.01), within six months of treatment outpatients received those 4.3 times more often (p ≤ 0.001) and anticoagulants-6.2 times (p ≤ 0.0001). After discharge, patients were assigned to therapy with statins 2.5 times more frequent in the second group of the patient population (p ≤ 0.01). Significant variables in therapeutic efficacy between patients in Group I and II have been established. Starting from 2017, the quality of ACVA medical care has significantly improved compared to that in 2009–2017.

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Keywords

Acute cerebrovascular accident, Stroke, Statins, Anticoagulants, Morisky Green scale.

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