Preparation, diagnoses of novel hetero atom compounds and evaluation the antibacterial activity of them Ayfan Abdulkareem Hamad1*, Muslim Rasim Farraj2**, Saleh Marwan Mahmood2 1College of Pharmacy, University Of Anbar, Anbar, Iraq 2Department of Environmental Sciences, College of Applied Sciences-Hit, University Of Anbar. *Corresponding Author E-mail: kareemhamad7@gmail.com
**dr.rasim92hmts@uoanbar.edu.iq
Online published on 22 April, 2021. Abstract This work included prepare of hetero atom compounds Ra1-Ra5from the interaction of prepared azomethines with anhydride compound. Azomethine compounds were prepared by condensation reaction. A number of new hetero atom compounds were prepared by acid-catalyzed Cycloaddition-reaction in anhydrous THF under reflux conditions. The formation of hetero ring has been achieved by Cycloaddition. The melting point, 1H-NMR, FT-IR and 13C-NMRspectroscopies technique were used to identified the final products. Biological activity of the prepared hetero compounds Ra1-Ra5 evaluated on E. Coli and S. aureus. Top Keywords Azomethine, 1, 3-oxazepin, Condensation reaction, Cycloaddition mechanism. Top |