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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2021, Volume : 14, Issue : 1
First page : ( 79) Last page : ( 84)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2021.00015.9

Preparation, diagnoses of novel hetero atom compounds and evaluation the antibacterial activity of them

Ayfan Abdulkareem Hamad1*, Muslim Rasim Farraj2**, Saleh Marwan Mahmood2

1College of Pharmacy, University Of Anbar, Anbar, Iraq

2Department of Environmental Sciences, College of Applied Sciences-Hit, University Of Anbar.

*Corresponding Author E-mail: kareemhamad7@gmail.com

**dr.rasim92hmts@uoanbar.edu.iq

Online published on 22 April, 2021.

Abstract

This work included prepare of hetero atom compounds Ra1-Ra5from the interaction of prepared azomethines with anhydride compound. Azomethine compounds were prepared by condensation reaction. A number of new hetero atom compounds were prepared by acid-catalyzed Cycloaddition-reaction in anhydrous THF under reflux conditions. The formation of hetero ring has been achieved by Cycloaddition. The melting point, 1H-NMR, FT-IR and 13C-NMRspectroscopies technique were used to identified the final products. Biological activity of the prepared hetero compounds Ra1-Ra5 evaluated on E. Coli and S. aureus.

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Keywords

Azomethine, 1, 3-oxazepin, Condensation reaction, Cycloaddition mechanism.

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