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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 9
First page : ( 4361) Last page : ( 4364)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00771.4

Different interaction analysis of strain CGSP14 in Streptococcus pneumoniae

Karavadi Balasankar1,*, Vinothkumar C2, Premalatha J3

1Department of Biomedical Engineering, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu-600 119

2Department of Electronics and Instrumentation Engineering, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu-600 119

3Department of Electronics and Communication Engineering, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu-600 119

*Corresponding Author E-mail: balasankar.bioinfo@sathyabama@ac.in

Online published on 16 September, 2020.

Abstract

Recognizing explicit ligands in CGSP14 Strain of streptococcus pneumonia utilizing virtual screening approach alongside the approval of ADMET descriptors. The objective successions were recovered from Uni Prot database,The homology demonstrating was performed by utilizing Modeler 9v7 which is trailed by confirmation utilizing Ramachandran plot, ligands and their analogs were acquired from Pubchem database,docking proteins and its separate analogs was performed by utilizing Discovery studio. Our Insilco examination delineate that proteins having a more prominent potential to progress toward becoming medication focus in CGSP14 Strain of streptococcus pneumonia and the above ligands having higher dock score might be considered as the potential lead particles for drug discovery.

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Keywords

Streptococcus pneumonia, CGSP14, Target, Protein, Ligand.

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