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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 7
First page : ( 3524) Last page : ( 3529)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00624.1

Targeted Drug Delivery through Nanosponges and its Approach

Praveen K.1,*, Balamurugan K.2

1M.Pharm., IInd Year, Department of Pharmacy, FEAT, Annamalai University, Annamali Nagar, Chidambaram-608002, Tamilnadu, India

2Associate Professor, Department of Pharmacy, FEAT, Annamalai University, Annamali Nagar, Chidambaram-608 002, Tamilnadu, India

*Corresponding Author E-mail: praveenspk071@gmail.com

Online published on 10 August, 2020.

Abstract

Efficient targeted drug transport approaches have been a dream for several decades. Nanosponge's drug transport system has emerged as one of the promising discipline in novel drug delivery technology. Recently the nanosponge drug delivery system has been big step to resolve the certain biopharmaceutical problems. The nanosponge targets the drug into the systemic circulation in the body until they encounter the particular targeted surface, and begin the release of drug in controlled drug and predictable way. Nanosponge's drug release systems were loaded with hydrophilic and lipophilic drug substance in a huge range drug molecule. Thus the nanosponge acts as suitable targeted carrier molecule. In the nanosponge technique the drug can be deliver in specific site, which prevent the drug, protein degradation, prolong drug release is a predictable way. Nanosponge technology is used to increasing the poor bioavailability of drug substance and the transport of drug into oral, parenteral as well as topical route. In the review article, the approaches for the preparation, evaluation and application of nanosponge were discussed.

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Keywords

Targeted drug delivery, Nanosponges, Polymer, Cross-linkers.

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