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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 7
First page : ( 3466) Last page : ( 3471)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00615.0

Ulcerative colitis: Treatment updates

Mahore Jayashri G.1,*, Deshpande Nupur V.1, Trivedi Rashmi V.2, Shelar Aniket S.1

1Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra, India

2SKB College of Pharmacy, New Kamptee, Nagpur

*Corresponding Author E-mail: jayashri.mahore@dypvp.edu.in

Online published on 10 August, 2020.

Abstract

Ulcerative Colitis is a disease which produces inflammation of the colon. Ulcerative Colitis causes inflammation and open sores called ulcers in the lining of the colon and the rectum. Intestinal microbiota plays an important role in the cause and progression of the disease. Various treatment strategies have been developed till date for ulcerative colitis. Use of steroidal drug is treatment of choice. But incomplete recovery and recurrence after treatment is major drawback of steroidal treatment. Ayurvedic medicines also have been used as supportive line of treatment but it is not a choice of treatment because of slow recovery. Nowadays use of prebiotic is emerging which mainly acts by manipulating disturbed microbiota and considered as a sound strategy for treating ulcerative colitis. Researchers have studied the effect of different prebiotics on ulcerative colitis and results were very promising. In the present review various treatment aspects of ulcerative colitis have been reviewed.

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Keywords

Intestinal bowel disorder, Ulcerative Colitis, Prebiotics, Microorganisms, Dextran sodium sulphate.

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