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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 7
First page : ( 3442) Last page : ( 3448)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00611.3

Nano Sponges: A Potential Drug Delivery Approach

Sadhasivam Janani, Sugumaran Abimanyu*, Narayanaswamy Damodharan

Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur-603203, India

*Corresponding Author E-mail: abipharmastar@gmail.com

Online published on 10 August, 2020.

Abstract

Recently, the progress in nanotechnology has led to the advancement of the delivery of drugs to the targeted site (TDDS). The introduction of Nano sponges has been an important step in conquering certain complications like toxicity of drug, its poor bioavailability, and release of medicament in a predictable manner. Currently, Nano sponges have achieved excellent impacts in delivering drugs through nanotechnology in which the nanosponges are porous in nature with tiny sponges (below 1 μm), circulating throughout the body. Therefore, they reach the target site and stick to the skin surface and release the drug in a controlled manner. A large variety of drugs can be encapsulated into the cavity of Nano sponges and it carries both hydrophilic and lipophilic drugs. Nano sponges (NSs) drug delivery system has been considered as one the most assuring field in pharmacy. It can be utilized as carrier for biocatalyst in the release of enzymes, vaccines, antibodies, and proteins. The current review focuses on the preparation method, evaluation and potential use in drug delivery system.

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Keywords

Nanosponges, controlled release, β cyclodextrin, topical application, cross-linkers, and polymers.

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