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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 7
First page : ( 3389) Last page : ( 3393)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00602.2

Preventive effect of Honey bee propolis on Salmonella enterica serovar Typhimurium infected BALB/c mice: A Hematological Study

Kalia Preeti1,*, Kumar Neelima R.2, Harjai Kusum3

1Department of Zoology, GGDSD College, Chandigarh, India

2Department of Zoology, Panjab University, Chandigarh, India

3Department of Microbiology, Panjab University, Chandigarh, India

*Corresponding Author E-mail: preeti.kalia84@gmail.com

Online published on 10 August, 2020.


Apitherapy is a branch of alternative medicine which deals with the therapeutic uses of all the honey bee or bee hive products. The present research aimed to study the effect of pretreated groups of experimental mice with one of the potent honey bee product i.e propolis and then infecting the animals with Typhoid causing bacteria i.e. Salmonella. Survival percentage, bacterial load and hematological parameters were observed. The bacterial load in blood and spleen was significantly reduced in case of propolis pretreated groups of mice. Moreover, the RBC count and WBC count in one of pretreated group was 8.4±0.52 million/mm3 and 7366.66±160.72/mm3 respectively which was significantly higher than that of infected control. So, from the results it was clearly evident that pretreatment with propolis decreases the severity of infection in mice.



Propolis, Salmonella, Preventive therapy, Bacteria, Hematology.


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