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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 7
First page : ( 3147) Last page : ( 3150)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00556.9

Studies on the Anti-inflammatory potential of selected medicinal plants in vitro

Kousalya K.1, Priya T.1, Venkatalakshmi P.1,2

1PG Research Department of Biochemistry, STET Women's College, Mannargudi

2Department of Biochemistry, PSG College of Arts and Science, Coimbatore

*Corresponding Author E-mail: venkatalakshmisathish@gmail.com

Online published on 10 August, 2020.

Abstract

Chronic inflammation is the underlying factor in causing multitude of human ailments ranging from arthritis to cancer. Amidst the emerging synthetic drugs, people started re-evaluating traditional plant based medicines because of the efficacy and safety of herbal medicine. Hence in the present study, efforts are made to validate the anti-inflammatory potential of four medicinal plants using in-vitro procedures. Ten different concentrations of aqueous extracts of selected medicinal plants ranging from 0.01–10mg/ml were taken. At a concentration of 10 mg/ml Erythrina indica has shown 74.15% of protein denaturation inhibition followed by Mukia maderaspatana (53%). Cardiospermum halicacabum has shown only 42.40% activity, whereas Delonix elata has shown only 14% activity. In the case of proteinase inhibition assay, Mukia maderaspatana at a concentration of 10 mg/ml has exhibited 74% inhibition of proteinase followed by Cardiospermum halicacabum 58%, Erythrina indica 38% and Delonix elata 30%. Among the four plants selected, except Delonix elata all the other three plants have revealed remarkable anti-inflammatory activity.

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Keywords

Chronic inflammation, Cardiospermum halicacabumDelonix elataErythrina indicaMukia maderaspatana.

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