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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 5
First page : ( 2065) Last page : ( 2068)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00371.6

Effect of Physiotherapy Intervention after Platelet Rich Plasma Procedure in Subjects with Grade 3 Osteoarthritis Knee

Sowmya M.V.*, Mangayarkarasi M

Department of Physiotherapy, SIMATS, Thandalam-602105

*Corresponding Author E-mail: sowmyamv83@gmail.com

Online published on 16 June, 2020.



To compare the effect with or without the physiotherapy intervention following the platelet Rich plasma therapy in subjects with grade 3 OA knee.


Osteoarthritis is a chronic degenerative conditions that results from breakdown of joint cartilage and underlying bone showing symptoms like pain, joint stiffness, swelling, joint deformity. Platelet Rich plasma is a concentrate of platelets obtained from one's own blood. Platelets have great potential in enhancing healing of muscles, tendon and ligaments. The growth factors released by platelets recruit reparative cells and may augment tissue repair and accelerate soft tissue healing.


30 subjects were selected based on the inclusion and exclusion criteria and the subjects were divided into 2 groups with 15 each as group A and group B. Physiotherapy treatment (stretching and strengthening exercises for quadriceps)was given after the PRP procedure to Group A from the day of procedure. Group B are treated medically(acetaminophen) without physiotherapy exercises after the PRP procedure.

Outcome Measures

Visual analog scale(VAS) and WOMAC scale were used as outcome measures.


Group A who have undergone physiotherapy treatment after PRP procedure is more significant(p value <0.0001) than the group B people who are treated medically without physiotherapy exercises.


The study concluded that the physiotherapy interventions are more effective when it i given after the PRP procedure by decreasing pain, stiffness and improving the patient's physical functions.



Osteoarthritis, Platelet rich plasma, Visual analogue scale, WOMAC scale.


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