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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 4
First page : ( 2045) Last page : ( 2052)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00368.6

Quercetin as Natural Bioavailability Modulator: An Overview

Bhimanwar Rachana*, Kothapalli Lata, Khawshi Akshay

Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune

*Corresponding Author E-mail: r.09joshi@gmail.com

Online published on 30 April, 2020.

Abstract

India is a country with variety of the medicinal herbs. Quest for safer and natural opinion for treatment of diseases led about 80% of world population to rely on herbal medicine. In advance drug design technology, a large number of drug molecules are being introduced every year but many have bioavailability issues with long lasting side effects. Low bioavailability leads to alteration in therapeutics efficacy of medicaments and cause hindrance encountered during new drug or drug product development. Thus there is need of molecules which when combine with other drugs enhance their bioavailability. Bioenhancers are such agents which by them when combined with active drugs lead to potentiation of pharmacological effect of drug by increasing bioavailability. Natural bioenhancers are the plant based molecules which promote biological activity or uptake of the drugs alone or in combination therapy. Along with piperine as Bioenhancer, proven in many cases there are many other natural constituent which possess Bioenhancer property. There is a vast array of unexploited plants which can be investigated for their drug bioenhancing potency. This article reviewed and emphasizes on the biopotentiator property of Quercetin. Quercetin is a plant pigment (flavonoid), found in many plants and foods, such as onions, green tea, apples and others. Buckwheat tea has a large amount of quercetin. Quercetin also has a as a medicinal benefits.

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Keywords

Bioenhancer, Quercetin, Bioavailability enhancement.

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