Antihyperglycemic Status of Coccinia grandis: An Extensive Overview Sunny Betsy1,*, Dr. Mathews Manju Maria2, Joseph Dhanish3, Mathew Flowerlet4, George Junia1, Varghese Bimi1 1Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala 2Associate Professor, Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala 3Assistant Professor, Department of Pharmaceutics, Nirmala College of Pharmacy, Muvattupuzha, Kerala *Corresponding Author E-mail: betsysunnye@gmail.com
Online published on 30 April, 2020. Abstract Plants are an exemplary source of medicine and have been used in healthcare since time immemorial. They are an efficacious remedy for multiple ailments. Coccinia grandis belonging to family Cucurbitaceae is a reservoir of medicinal properties. It is being regarded as a universal panacea in Ayurvedic medicines. Extracts made from the various parts of the plant mainly leaf and fruit have significant analgesic, anti-inflammatory, antimicrobial, antidiabetic, antioxidant, hepatoprotective, anticancer, mutagenic activity, etc. in different animal models. Coccinia grandis contain copious amounts of phytoconstituents like flavonoids, saponins, glycosides, alkaloids, phenols, etc. which heavily contribute to the diverse pharmacological activities. In this study, the focus is given to Coccinia grandis as a better herbal substitute for synthetic counterparts in antihyperglycemic therapy. Top Keywords Coccinia grandis, Cucurbitaceae, ayurvedic medicine, animal models, antihyperglycemic. Top |