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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 3
First page : ( 1289) Last page : ( 1292)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00237.1

In-Vitro Evaluation of Anti-Urolithic Activity of Leaves Extract of Costus igneus

Kushagra D.*, Rajiv S., Ruchi G., Neelesh M

Smriti College of Pharmaceutical Education, MR-11, Dewas Naka, Indore-452010, India

*Corresponding Author E-mail: kushu0129@gmail.com

Online published on 22 April, 2020.

Abstract

Recent advances in drug therapy has tremendously increased due to its demand with the ever growing health care needs. Occurrence of many dreadful diseases including liver, kidney, heart disorders are now a day's very common and people prefer modern medicines as compare to conventional medicines. But Scientific knowledge and exploration and technological advancements had made plant derived medicine as a choice of therapy in many ailments. Many novel and safe herbal preparations are effectively used in treatment. Urolithiasis is common condition of development of calculi or stone in urinary system specially ureter and gall bladder. Many Herbal formulations like neeri, cystone etc. are widely available in the market and has proven potential in the management of disease. In the present investigation methanolic extract of leaves of Costus igneus was used to analyse its In-vitro anti-urolithic activity. The percentage dissolution of calcium oxalate in the presence of extract in semipermeable egg membrane was studied and compared with standard drug cystone. The percentage dissolution of methanolic extract and standard drug cystone was found to be 86.12% and 80.34% respectively. The results suggests that the plant can be used for the effective treatment of urolithiasis and can be added in the preparation of polyherbal formulation.

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Keywords

Urolithiasis, Costus igneus, In-vitro studies, calcium oxalate, percentage dissolution.

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