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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 3
First page : ( 1193) Last page : ( 1197)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00220.6

Synergistic Antioxidant activity of a Polyherbal Preparation

Choudhari Ganesh1,3,*, Choudhari Vishnu1,3, Baheti Akshay1,3, Mantri Manini1, Matapurkar Savita1, More Chandrakant2

1MAEER's Maharashtra Institute of Pharmacy, Pune-411038, Maharashtra, India

2Shri Swami Samarth Ayurvedic Pharmaceuticals, Trimbakeshwar, Dist. Nashik-422212, Maharashtra, India

3School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, MIT Campus, Kothrud, Pune-411038, Maharashtra, India

*Corresponding Author E-mail: choudhariganesh@gmail.com

Online published on 22 April, 2020.

Abstract

Exogenous or external antioxidants are required in the form of a food supplements and/or medicines to protect the body from oxidative stress and ultimately from heart disease, stroke, aging and other risks specially cancer. A liquid polyherbal preparation was developed as Saptarangi Plus Kadha which contains three medicinally important herbs such as Salacia chinensis, Curcuma longa and Tinospora cordifolia. The antioxidant activity of Saptarangi Plus Kadha and individual extracts of the said three herbs were carried out by antioxidant capacity assays such DPPH (1, 1-diphenyl-2-picrylhydrazyl radical), FRAP (Ferric reducing antioxidant power) and H2O2 scavenging. The absorbance was measured on UV spectrophotometer at required wavelengths and IC50 values were calculated for Saptarangi Plus Kadha and individual extracts. The individual herbs in combination showed a good synergistic antioxidant activity in SK. Hence, the results are superior for Saptarangi Plus Kadha over individual extracts of the said three herbs. Thus the results of the study proved that Saptarangi Plus Kadha has synergistic antioxidant potential than individual extracts of the said three herbs which indicates further exploration of research work.

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Keywords

Synergistic antioxidant activity, polyherbal preparation, saptarangi, FRAP, DPPH, H2O2 scavenging.

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