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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 2
First page : ( 850) Last page : ( 852)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00160.2

Anti-microbial Studies of Potential Cyclopentanone derived Spiropyrroidines

Badaghu Karunakar, Gavaskar D.*

Department of Chemistry, School of Basic Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Pallavaram

*Corresponding Author E-mail: gavas.sbs@velsuniv.ac.in

Online published on 9 April, 2020.

Abstract

A Series of Various cyclopentanone derived spiro-pyrrolidines were synthesized using 1, 3-dipolar cycloaddition methodology. The compounds found to have very good antimicrobial properties and some of the compounds shown properties greater than the reference compounds. The attachment of cyclopentanone moiety to spiropyrrolidines enhanced the antimicrobial properties and it is shown in the results.

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Keywords

Nutrient agar, bacterial culture, spiropyrrolidines, well diffusion method.

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