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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 2
First page : ( 679) Last page : ( 681)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00130.4

The Effect of Oral Administration of Ipomoea batatas L. Leaves Etanolic Extract on Hematological Profile in Rats

Saputra Anak Agung Bagus Yoga1,2, Putra Dewa Gede Purnama1,2, Putra I Putu Yogi Astara1,2, Warditiani Ni Kadek1,*

1Department of Pharmacy, Mathematics and Natural Science Faculty, Udayana University, Indonesia

2Institute Forensic Science and Criminatology, Udayana University, Bali, Indonesia, 80361

*Corresponding Author E-mail: kadektia@unud.ac.id

Online published on 9 April, 2020.


Sweet potato (Ipomoea batatas L.) leaves have been shown to have anti-diabetic, anti-inflammatory, anti-mutagenic, antioxidant, anticancer activities, wound healing. However, there is no research on the effect of ethanolic extract of I. batatas L. leaves on hematological profiles; hence, such research needs to be conducted. The study was carried out by administering a variety of dose of the ethanolic extract of I. batatas L. leaves from maceration results to several groups of rats during 28 days of treatment. Each group consisted of 7 rats with group distribution as follows: normal control (without treatment), negative control (given distilled water), treatment groups (group given extract at a dose of 10 mg/kg body weight, 100 mg/kg body weight, and 1000 mg/kg body weight). The results of an examination of rats ’hematological profiles showed that the group given the extract with 1000 mg/kg body weight dose had hemoglobin levels and number of red blood cells that significantly higher (P<0.05) compared to the other groups. Based on this, the ethanolic extract of I. batatas L. leaves have the potential to increase hemoglobin and erythrocyte levels.



I. batatas L. Ethanolic Extract, Hematological Profile, Rats.


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