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Year : 2020, Volume : 13, Issue : 12
First page : ( 6276) Last page : ( 6283)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.01092.6

An outline on curcumin: Its pro-liposome and liposome formulations

Yadav Chandan1, Asif Md.1, Akhtar Juber1*, Badruddeen1, Khan Mohammad Irfan1, Saquib1, Tanweer1, Ahmad Mohammad1, Rind Laiba1

1Department of Pharmacy, Integral University, Kursi Road, Lucknow (Uttar Pradesh) -226026India.

*Corresponding Author E-mail: juberakhtar@gmail.com

Online published on 15 February, 2021.


Curcumin (Cur) is broadly accepted for its useful functions. Cur has low water solubility therefore its application in drug delivery became a challenge for researchers. To overcome the absorption, bioavailability and overall biochemical/structural degradation we may develop pro-liposomes and liposomes of Cur. The proliposomes generally administrated by orally, topically and parentally and mainly used in cosmetic and hair technologies, diagnostic purpose, sustained release formulations and as good carriers in gene delivery. This review highlights the speculative approach and some new advancement for the preparation of pro-liposomes in general. Various methods to formulate pro-liposomes (Film-deposition carrier method, Spray drying method, Fluidized-bed method, Supercritical anti-solvent method), evaluation parameters (Hydration study, Zeta potential, Flow property) there of and applications of pro-liposome are highlighted. This may help for further preparation and evaluation of Cur. based formulations. Additionally different features of curcumin related to its pharmacological profile and mechanism of protection in various ailments have been reported.



Curcumin, Liposome, Pro-liposome, Solubility.


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