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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2020, Volume : 13, Issue : 12
First page : ( 6218) Last page : ( 6223)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.01084.7

Partial characterization of green synthesized silver nanoparticles of Cardiospermum halicacabum and Butea monosperma aqueous extract combination (CHBMCSNP)

Rameshwari K. Sudha1*, Abirami M.1, Christobel R. Gloria Jemmi1

1Department of Biochemistry (PG), V.V. Vanniaperumal College for women, Virudhunagar, Tamil Nadu, India.

*Corresponding Author E-mail: sudharameshwari@vvvcollege.org

Online published on 15 February, 2021.

Abstract

This study focuses on synthesis of silver nanoparticle (NP) from the combination of two plant extracts (Cardiospermum halicacabum (CH) and Butea monosperma (BM)) and their structural elucidation and antioxidant activity. The presence of the identified phytochemicals makes them elucidate structurally by UV, FTIR, SEM and XRD. The nano particle synthesized was confirmed by UV-Visible spectrum which gives a sharp band around at 430nm. The FTIR analysis of synthesized nanoparticles revealed prominent peaks at 1631.52 cm−1, 2147.12 cm−1 and 3370.56 cm−1 corresponds to N-H bending of primary amines. The absorption peaks obtained at 2146 cm−1 assigned to C=C stretching of alkynes. These observations indicate the presence of and binding of proteins with silver nanoparticles which can lead to their possible stabilization. SEM analysis shows that relatively spherical and uniform silver nanoparticles were formed with diameter of 11 to 13.81nm. XRD analysis shows particle size 5.2nm. Moreover CHBMCSNP exhibited optimum antioxidant activity. However, further investigations were needed to identify the scaling up of this extract on silver nanoparticles synthesis and its application on Rheumatoid Arthritis.

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Keywords

Silver nanoparticle, FTIR, SEM, XRD, Antioxidant activity, Cardiospermum halicacabum, Butea monosperma.

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