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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2020, Volume : 13, Issue : 12
First page : ( 5972) Last page : ( 5978)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.01042.2

Green synthesis, characterization and application study of zinc nano particles synthesized using aqueous root extract of Sphagneticola trilobata lin

Mathin SK. Abdul1*, Raju M. David2, Reddy D. Rama Sekhara3

1Department of Basic Sciences and Humanities, Gudlavalleru Engineering College, Gudlavalleru-521356, Andhra PradeshIndia.

2Department of Chemistry, P. B. Siddhartha College of Arts and Sciences, Vijayawada-521010, Andhra PradeshIndia.

3Department of Chemistry, Krishna University, Machilipatnam-521001, Andhra PradeshIndia.

*Corresponding Author E-mail: abdulmathin786@gmail.com

Online published on 15 February, 2021.

Abstract

In the present investigation, we have described the green biosynthesis of Zinc nanoparticles (ZnNPs) using aqueous root extract of Sphagneticola trilobata Lin as capping agent. The antioxidant, anti-diabetic and antimicrobial activities of ZnNPs was also studied. The Scanning Electron Microscopy analysis (SEM) results confirmed the irregular shaped of AgNPs with difference sizes of the particles and an average from 65–80 nm. X-ray diffraction (XRD) result confirmed the characteristic peaks indicated at 111, 200, 221 and 311 crystal planes for the crystalline of the face centered cubic lattice. Further, aqueous root extract extract and ZnNPs were evaluated to assess their antioxidant potential using various in vitro systems such as using 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2, 2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and Hydroxyl radical scavenging activity. The anti-diabetic and anti-inflammatory activity of the aqueous root extract and ZnNPs were also studied and the results confirm the Zinc nano particles synthesized using aqueous root extract of Sphagneticola trilobata Lin were found to having enhanced pharmacological activities.

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Keywords

Sphagneticola trilobata, Green synthesis, Nickel nano particles, DPPH activity, Pharmacological activities.

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