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RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY
Year : 2020, Volume : 13, Issue : 12
First page : ( 5754) Last page : ( 5756)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.01002.1

Translocation of C-MYC gene by expressed eighty percentage of tumour cells cause abdominal burkitt's lymphoma during the third phase of chemotherapy it relapsed: A case report and literature

Kiran G. Sai1, Puja U. Sahithi2*, Kumar Doondi Phani2, Pravalika A.2, Sai Ch. Bhargav2

1Assistant Professor, Department of Pharmacy Practice, Nirmala College of Pharmacy, Atmakur, Mangalagiri, Guntur (Dist)-522503Andhra PradeshIndia.

2Pharm D Students, Nirmala College of Pharmacy, Atmakur, Mangalagiri, Guntur (Dist)-522503Andhra PradeshIndia.

*Corresponding Author E-mail: uppaluru.sahithipuja@gmail.com

Online published on 15 February, 2021.

Abstract

Denis Burkitt found the first case of a "lymphoma" in children from the region of Africa, which double its size every 24 hours. A Nineteen years male adolescent was admitted in the hospital with the chief complaints of highgrade fever along with Fatigue, Giddiness. The most common treatment for BL is intensive chemotherapy, which usually lasts for a month, but may also last up to 8 months. Children with BL having survival rates better than adults. Burkitt's lymphoma is associated with a particular translocation t(8:14)(q24:q23) that juxtaposes the MYC/c-Myc gene (8q24). It represents around half of all malignant non-Hodgkin's lymphoma in children and around 2% in adults in Europe and North America. In Africa, BL accounts for 30–50% of all childhood cancer. the standard treatment for BL is intensive chemotherapy, which usually lasts for a month, but may also last up to 8 months. When diagnosed early, the survival rate higher than 90%. Most of the physicians will choose chemotherapy and some other treatment options based on disease complexity and patient progress. This information might be helpful.

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Keywords

Burkitt's lymphoma, Children, MYC-gene translocation, Chemotherapy complications.

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