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Research Journal of Pharmacy and Technology
Year : 2020, Volume : 13, Issue : 10
First page : ( 4591) Last page : ( 4593)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2020.00808.2

Anti-inflammatory activity of Ginger oleoresin mediated Silver nanoparticles

Swathy S1, Roy Anitha2,*, Rajeshkumar S.2

1Graduate Student, Bachelor of Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India

2Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India

*Corresponding Author E-mail: anitharoy2015@gmail.com

Online published on 28 October, 2020.

Abstract

Background

Ginger, belonging to the family Zingiberaceae, is known for its anti -inflammatory and anti- microbial activities since ancient times. Ginger Oleoresin, extract of ginger, has the properties of ginger and was used in this study for its anti- inflammatory properties. Aim: The aim of the study was to evaluate the anti- inflammatory activity of ginger oleoresin mediated silver nanoparticles.

Materials and Methods

Ginger oleoresin was used to prepare the silver nanoparticle which was confirmed by UV-Vis spectrophotometer. The anti -inflammatory test was carried out by inhibition of albumin denaturation assay technique and was compared with standard diclofenac sodium.

Results

A concentration dependent increase in the anti-inflammatory activity was evident in both nanoparticles and the standard in this study. The anti-inflammatory activity of ginger oleoresin mediated nanoparticles was similar to that of the standard diclofenac sodium.

Conclusion

The study has proved that ginger oleoresin can be used for the eco-friendly green synthesis of silver nanoparticles and as ginger oleoresin mediated silver nanoparticles showed good used anti-inflammatory activity, it may be used for various inflammatory conditions.

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Keywords

Anti- inflammatory, Ginger, Nanoparticles, Oleoresin, Spectroscopy.

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