Influence of Aminotransferase Enzyme on Delayed Onset Muscle Soreness among Novice Athletes: A Pilot Single-Blind Randomized Clinical Trial Sudhakar Selvaraj1,*, Paul Jibi2, Selvam P Senthil3, Mahendranath P4 1Associate Professor, Faculty of Physiotherapy, Dr. M. G. R. Educational and Research Institute, Maduravoyal, Chennai– 600095, Tamil Nadu, India 2Professor, Faculty of Physiotherapy, Dr. M. G. R. Educational and Research Institute, Maduravoyal, Chennai– 600095, Tamil Nadu, India 3Professor, School of Physiotherapy, VELS Institute of Science, Technology & Advanced Studies, Pallavaram, Chennai-600043, Tamil Nadu, India 4Associate Professor, Department of Pathology, A.C.S Medical College and Hospital, Dr. M. G. R. Educational and Research Institute, Velappanchavadi, Chennai-600 077, Tamil Nadu, India *Corresponding Author E-mail: sudhakar.physio@drmgrdu.ac.in
Online published on 24 December, 2019. Abstract Introduction Delayed onset muscle soreness (DOMS) is a familiar experience for the elite as well as the novice athlete. One of the most popular concepts in the lay exercise community is that delayed soreness is a result of metabolic waste product accumulation in the muscles. Objective To evaluate the pattern of changes in serum aminotransferase level after performing a different intensity of eccentric exercises and to find a suitable percentage of one repetition maximum (1RM) to be selected for inducing delayed onset muscle soreness (DOMS). Materials and Methods A total of 48 novice athletes was selected and a simple random sampling technique with the lottery method was adopted to participate in this three group, a pilot single-blind, randomized clinical study. After collection of demographic data, the athletes were allotted to the group based on the chits what they have picked. Group A consists 70% of 1 RM, Group B consist 80% of 1 RM and Group C consist 90% of 1 RM taken for the induction of Delayed Onset Muscle Soreness (DOMS) experimentally. Blood samples were collected at the baseline and 24 hours,48 hours,72 hours & 96 hours after inducing DOMS. Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) were considered as dependent variables and values displayed in the instrument were noted. Results Repeated measures ANOVA and one-way analysis of variance were adopted to analyse the statistical difference between the groups. The p-value less than 5% (0.05) is considered to be significant. There exists no significant difference between the three groups at baseline to 24 hour measurements at (P > 0.05). On the other hand, a statistically significant difference was found between three groups at 48 hours,72 hours & 96 hours at (P < 0.05). Conclusion Based on the changes occurred in serum aminotransferase levels, the study concluded that 80% of 1 RM were experimentally a standardized procedure for the induction of DOMS. Top Keywords Delayed Onset Muscle Soreness, Repetition Maximum, Alanine aminotransferase, Aspartate aminotransferase. Top |