The use of Biomarkers in blood serum as identifiers of the influence of production factors on prevalence of Atrophic gastritis Kotelevets Sergey M.1,*, Chekh Sergey A.2 1North Caucasus State Academy of Humanities and Technology, Medical Institute, PhD in Medical Sciences, Professor, Cherkessk, Russian Federation 2North Caucasus State Academy of Humanities and Technology, Head of Department of Information Systems, Cherkessk, Russian Federation *Corresponding Author E-mail: smkotelevets@mail.ru
Online published on 24 December, 2019. Abstract This article is based on clinical examinations of patients and determines the effect of occupational hazards at industrial enterprises of the Karachayevo-Cherkessian Republic on the prevalence of severe gastric atrophy. Materials and Methods A total of 677 persons were examined for markers of gastric atrophy, of which 60% were employees of industrial enterprises, exposed to factors of technospheric hazards at the industrial enterprises, and the rest had never been exposed to them. Results We determined the pathogenic influence of production factors on the prevalence of atrophic gastritis. The prevalence of atrophic gastritis is higher among men than among women. The prevalence of atrophic gastritis increases with age among patients of both sexes. Conclusions For industrial workers who had been exposed for a long time to production factors, the prevalence of atrophic gastritis is significantly higher compared to those who had never been exposed to occupational hazards. We found that it was severe gastric atrophy that causes a high risk of gastric cancer at industrial enterprises of the Karachayevo-Cherkessian Republic. Top Keywords Stomach cancer, biomarkers, blood serum, technospheric hazard factors, prevalence of atrophic gastritis. Top |