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Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 8
First page : ( 4052) Last page : ( 4056)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.5958/0974-360X.2019.00698.X

Dental pulp Stem Cells in Regenerative Medicine – A Literature Review

Timothy Chris Noel1,*, Samyuktha P.S.1, Dr. Brundha M.P.2

1Undergraduate Student, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Chennai, 600077, Tamil nadu, India

2Department of Pathology, Saveetha Institute of Medical and Technical Science, 162, Poonamallee High Road, Chennai, 600077, Tamil nadu, India

*Corresponding Author E-mail: generalpath2015@gmail.com

Online published on 24 December, 2019.


Stem cells are unspecialized cells that have a property of differentiating into specific specialized cell types. They also have a self-renewal property. Stem cells are identified in various human adult tissues including adipose tissue, skin, blood, bone marrow, hair follicles and dental pulp. Stem cell research has undergone rapid development owing to its usefulness in regenerative therapies for various neurological and genetic disorders. Previous Studies have shown that the dental pulp tissue can also be used to derive Mesenchymal Stem Cells (MSCs) when tissue is grown in culture. These MSCs can differentiate into several cell types. It is proposed that dental pulp stem cells (DPSCs) can develop Induced Pluripotent Stem Cells (iPSCs) which can be used for therapies of various diseases. This study has a primary focus on Dental Pulp Stem Cells and its various uses and Advancements in regenerative medicine. Nevertheless, it is still a fairly recent discovery and therefore requires further research on its biological capability, regenerative property, etc. until it is introduced into everyday medical practices.



Pulp, Teeth, Stem cells, Regeneration, Differentiation.


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